Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.51 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.51 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.51 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954459 | 0.99 | KDM4E (0.57) | KDM4EMEN1RECQLKMT2ATHRA | |
| SCHEMBL7956498 | 0.87 | KDM4E (0.54) | KDM4EMEN1RECQLKMT2ATHRA | |
| SCHEMBL28008265 | 0.87 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2ATHRA | |
| SCHEMBL28366897 | 0.87 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2ATHRA | |
| SCHEMBL27761606 | 0.87 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2ATHRA | |
| SCHEMBL28210406 | 0.87 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2ATHRA | |
| SCHEMBL31396225 | 0.87 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2ATHRA | |
| SCHEMBL28371003 | 0.87 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2ATHRA | |
| SCHEMBL28575933 | 0.87 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2ATHRA | |
| SCHEMBL7954462 | 0.86 | KDM4E (0.55) | KDM4EMEN1RECQLKMT2ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |