Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.39 |
| ▸ | PTGIR | P43119 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963138 | 0.85 | TBXA2R (0.56) | MEN1KMT2AKDM4CTBXA2RPTGIR | |
| SCHEMBL7958632 | 0.74 | TBXA2R (0.44) | MEN1KMT2AKDM4CTBXA2RPTGIR | |
| SCHEMBL7959853 | 0.69 | TBXA2R (0.40) | MEN1KMT2AKDM4CTBXA2RPTGIR | |
| SCHEMBL27516798 | 0.68 | KDM4C (0.60) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL9084486 | 0.67 | KDM4C (0.49) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL4991401 | 0.67 | MEN1 (0.44) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL7948790 | 0.66 | SMN1; SMN2 (0.41) | MEN1KMT2ATBXA2RPTGIR | |
| SCHEMBL7221504 | 0.66 | HPGD (0.44) | MEN1KMT2A | |
| SCHEMBL10974334 | 0.65 | KDM4C (0.40) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL11636149 | 0.65 | MEN1 (0.58) | MEN1KMT2AKDM4CADORA3EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |