Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 10/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958339 | 0.84 | PTGIR (0.36) | PTGIRTBXA2RMEN1KMT2APTPN1 | |
| SCHEMBL7958407 | 0.82 | KDM4C (0.36) | PTGIRTBXA2RMEN1KMT2APTPN1 | |
| SCHEMBL7221504 | 0.81 | HPGD (0.44) | MEN1KMT2APTPN1 | |
| SCHEMBL7948483 | 0.74 | PSMB8 (0.56) | SMN1; SMN2PTGIRTBXA2RMEN1KMT2A | |
| SCHEMBL7952633 | 0.74 | KDM4C (0.33) | PTGIRTBXA2R | |
| Hydrochloric Acid SCHEMBL10671160 | 0.73 | PSMB8 (0.55) | SMN1; SMN2PTGIRTBXA2RMEN1KMT2A | |
| SCHEMBL16861344 | 0.72 | HPGD (0.42) | MEN1KMT2APTPN1KDM4E | |
| SCHEMBL9535725 | 0.72 | KDM4E (0.44) | MEN1KMT2AKDM4E | |
| SCHEMBL10918433 | 0.70 | HPGD (0.43) | MEN1KMT2APTPN1 | |
| SCHEMBL11771086 | 0.69 | DHFR (0.53) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |