Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 9/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7959211 | 0.87 | NPY1R (0.61) | NPY1RTSHRKDM4EALOX15TDP1 | |
| Hydrochloric Acid SCHEMBL7949110 | 0.86 | NPY1R (0.58) | NPY1RTSHRKDM4EALOX15TDP1 | |
| SCHEMBL7963340 | 0.85 | NPY1R (0.57) | NPY1RTSHRKDM4EALOX15TDP1 | |
| SCHEMBL7948979 | 0.85 | NPY1R (0.67) | NPY1RTSHRKDM4EALOX15TDP1 | |
| SCHEMBL7963645 | 0.82 | NPY1R (0.70) | NPY1RTSHRKDM4EALOX15TDP1 | |
| Hydrochloric Acid SCHEMBL7960173 | 0.81 | NPY1R (0.59) | NPY1RTSHRKDM4EALOX15TDP1 | |
| SCHEMBL7960741 | 0.81 | NPY1R (0.58) | NPY1RTSHRKDM4EALOX15TDP1 | |
| SCHEMBL7959489 | 0.79 | NPY1R (0.60) | NPY1RTSHRKDM4EALOX15TDP1 | |
| SCHEMBL7963425 | 0.79 | NPY1R (1.00) | NPY1RTSHRHTR5AALDH1A1HSD17B10 | |
| SCHEMBL7960734 | 0.79 | NPY1R (0.65) | NPY1RTSHRKDM4EALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |