Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 7/20 | 0.65 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27479054 | 0.92 | NPY1R (0.61) | NPY1REGFRFFAR1FFAR4BCL2 | |
| SCHEMBL7959769 | 0.89 | NPY1R (0.62) | NPY1REGFRBCL2MCL1KDM4E | |
| SCHEMBL7963655 | 0.87 | NPY1R (0.60) | NPY1RBCL2MCL1KDM4EALOX15 | |
| SCHEMBL7963645 | 0.83 | NPY1R (0.70) | NPY1RBCL2MCL1KDM4EALOX15 | |
| SCHEMBL7958718 | 0.81 | NPY1R (0.62) | NPY1REGFRBCL2MCL1KDM4E | |
| SCHEMBL7948979 | 0.81 | NPY1R (0.67) | NPY1RKDM4EALOX15TSHRTDP1 | |
| SCHEMBL7960758 | 0.80 | NPY1R (0.57) | NPY1RALDH1A1HPGD | |
| SCHEMBL7958788 | 0.79 | NPY1R (0.62) | NPY1RBCL2MCL1KDM4EALOX15 | |
| SCHEMBL7956731 | 0.79 | NPY1R (0.65) | NPY1RKDM4EALOX15TSHRTDP1 | |
| SCHEMBL7959923 | 0.79 | NPY1R (1.00) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| EP-0789688-A4 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0789688-A1 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1997009308-A1 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |