Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 9/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | USP14 | P54578 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957295 | 0.84 | NPY1R (0.87) | NPY1RMEN1KMT2AALDH1A1USP14 | |
| SCHEMBL7956831 | 0.83 | NPY1R (0.75) | NPY1RMEN1KMT2AUSP14 | |
| SCHEMBL7963329 | 0.82 | NPY1R (1.00) | NPY1RUSP14 | |
| SCHEMBL7960383 | 0.81 | NPY1R (0.77) | NPY1RKMT2AALDH1A1MAPK1LMNA | |
| Hydrochloric Acid SCHEMBL7959234 | 0.81 | NPY1R (0.98) | NPY1RUSP14 | |
| SCHEMBL7958718 | 0.80 | NPY1R (0.62) | NPY1RMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7958788 | 0.78 | NPY1R (0.62) | NPY1RMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7956872 | 0.78 | NPY1R (0.60) | NPY1RUSP14 | |
| SCHEMBL7949133 | 0.76 | NPY1R (0.65) | NPY1RMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27493915 | 0.76 | NPY1R (0.74) | NPY1RUSP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| CN-1173867-A | Indolyl neuropeptide Y receptor antagonists | LILLY CO ELI (US) | 1998-02-18 | — | — | CN | disclosed |