Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 11/20 | 1.00 |
| ▸ | USP14 | P54578 | 6/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7959234 | 0.99 | NPY1R (0.98) | NPY1RUSP14HRH3SMN1; SMN2 | |
| SCHEMBL7957295 | 0.93 | NPY1R (0.87) | NPY1RUSP14SMN1; SMN2 | |
| SCHEMBL27559242 | 0.88 | NPY1R (0.79) | NPY1RUSP14HRH3 | |
| SCHEMBL7956887 | 0.88 | NPY1R (0.78) | NPY1RUSP14HRH3SMN1; SMN2 | |
| SCHEMBL7957128 | 0.88 | NPY1R (0.84) | NPY1RHRH3SMN1; SMN2 | |
| SCHEMBL7963164 | 0.86 | NPY1R (1.00) | NPY1RHRH3SMN1; SMN2 | |
| SCHEMBL7956831 | 0.86 | NPY1R (0.75) | NPY1RUSP14 | |
| SCHEMBL27493915 | 0.85 | NPY1R (0.74) | NPY1RUSP14 | |
| SCHEMBL7959094 | 0.85 | NPY1R (1.00) | NPY1RUSP14HRH3 | |
| SCHEMBL7949040 | 0.83 | NPY1R (0.91) | NPY1RHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| CN-1173867-A | Indolyl neuropeptide Y receptor antagonists | LILLY CO ELI (US) | 1998-02-18 | — | — | CN | disclosed |