Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 12/20 | 0.78 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP14 | P54578 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963329 | 0.88 | NPY1R (1.00) | NPY1RHRH3SMN1; SMN2USP14 | |
| Hydrochloric Acid SCHEMBL7959234 | 0.87 | NPY1R (0.98) | NPY1RHRH3SMN1; SMN2USP14 | |
| SCHEMBL7957128 | 0.86 | NPY1R (0.84) | NPY1RHRH3SMN1; SMN2 | |
| SCHEMBL7960575 | 0.85 | NPY1R (0.82) | NPY1RHRH3 | |
| SCHEMBL7959646 | 0.84 | NPY1R (0.60) | NPY1RTP53 | |
| SCHEMBL7957295 | 0.84 | NPY1R (0.87) | NPY1RSMN1; SMN2USP14 | |
| SCHEMBL7963164 | 0.84 | NPY1R (1.00) | NPY1RHRH3SMN1; SMN2 | |
| SCHEMBL7961002 | 0.82 | NPY1R (0.57) | NPY1RTP53 | |
| SCHEMBL27493915 | 0.82 | NPY1R (0.74) | NPY1RUSP14TP53 | |
| SCHEMBL7959355 | 0.81 | NPY1R (0.59) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | claimed |
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| EP-0789688-A4 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0789688-A1 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1997009308-A1 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |