Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 6/20 | 0.57 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949157 | 0.94 | NPY1R (0.56) | NPY1RALDH1A1HSD17B10KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL7948522 | 0.93 | NPY1R (0.55) | NPY1RALDH1A1HSD17B10MAPT | |
| SCHEMBL8801207 | 0.88 | NPY1R (0.56) | NPY1R | |
| SCHEMBL7959480 | 0.84 | NPY1R (0.51) | NPY1RALDH1A1MEN1KMT2A | |
| SCHEMBL7959706 | 0.83 | NPY1R (0.55) | NPY1RALDH1A1HSD17B10KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL7957055 | 0.83 | NPY1R (0.55) | NPY1RALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL7958788 | 0.83 | NPY1R (0.62) | NPY1RALDH1A1KDM4EALOX15TSHR | |
| SCHEMBL7949133 | 0.83 | NPY1R (0.65) | NPY1RALDH1A1HSD17B10KDM4EALOX15 | |
| SCHEMBL7957061 | 0.83 | NPY1R (0.54) | NPY1RUTS2RALDH1A1HSD17B10KDM4E | |
| SCHEMBL7957083 | 0.83 | NPY1R (0.54) | NPY1RALDH1A1HSD17B10KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |