SCHEMBL795785

SCHEMBL795785

CN([SiH3])[Si](C)(C)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4778725 0.78
SCHEMBL23404261 0.75
Pyridine SCHEMBL8381377 0.74 TSHR (0.41)
SCHEMBL303170 0.73
SCHEMBL232898 0.73
SCHEMBL15015774 0.70
SCHEMBL9615199 0.70
SCHEMBL20578017 0.67 ALDH1A1 (0.39)
Ammonia Solution, Strong SCHEMBL9230728 0.66
Ammonia Solution, Strong SCHEMBL29181788 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0624161-A1 2'-DESOXY-ISOGUANOSINES, ISOSTER ANALOGUES AND ISOGUANOSINE DERIVATES AND THEIR USE Roche Diagnostics GmbH (DE) 1994-11-17 EP claimed
WO-1993012130-A1 2'-DESOXY-ISOGUANOSINES, ISOSTER ANALOGUES AND ISOGUANOSINE DERIVATES AND THEIR USE BOEHRINGER MANNHEIM GMBH (DE) 1993-06-24 WO claimed
JP-8176462-A None JP disclosed
CN-115504865-A Method for catalytically synthesizing oligoglycerol by solid base catalyst 广东工业大学 2022-12-23 CN disclosed
WO-2012036445-A4 CATALYST FOR SELECTIVE OXIDATIVE DESULFURIZATION AND PREPARATION METHOD THEREOF 한국화학연구원 (KR) 2012-08-09 WO disclosed
WO-2012036445-A2 CATALYST FOR SELECTIVE OXIDATIVE DESULFURIZATION AND PREPARATION METHOD THEREOF 한국화학연구원 (KR) 2012-03-22 WO disclosed
US-6498241-B1 2-deoxy-isoguanosines isosteric analogues and isoguanosine derivatives as well as their synthesis ROCHE DIAGNOSTICS GMBH (DE) 2002-12-24 US disclosed
US-6147199-A 2-deoxy-isoguanosines isoteric analogues and isoguanosine containing oligonucleotides BOEHRINGER MANNHEIM (DE) 2000-11-14 US disclosed
EP-0624161-B1 2'-DESOXY-ISOGUANOSINES, ISOSTER ANALOGUES AND ISOGUANOSINE DERIVATES AND THEIR USE BOEHRINGER MANNHEIM GMBH (DE) 1999-02-24 EP disclosed
JP-H08176462-A PARTIALLY HYDROPHOBIC PRECIPITATED SILICIC ACID NIPPON SILICA IND CO LTD 1996-07-09 JP disclosed
EP-0624161-A1 2'-DESOXY-ISOGUANOSINES, ISOSTER ANALOGUES AND ISOGUANOSINE DERIVATES AND THEIR USE Roche Diagnostics GmbH (DE) 1994-11-17 EP disclosed
WO-1993012130-A1 2'-DESOXY-ISOGUANOSINES, ISOSTER ANALOGUES AND ISOGUANOSINE DERIVATES AND THEIR USE BOEHRINGER MANNHEIM GMBH (DE) 1993-06-24 WO disclosed
US-4773985-A Method of optimizing mesophase formation in graphite and coke precursors UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1988-09-27 US disclosed
US-4123547-A ANTIBIOTICS MERCK & CO., INC. (US) 1978-10-31 US disclosed