Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954094 | 0.91 | OPRK1 (0.32) | CNR2CYP3A4CYP2D6NFKB1OPRK1 | |
| SCHEMBL7946822 | 0.89 | OPRK1 (0.34) | CNR2CYP3A4CYP2D6NFKB1OPRK1 | |
| SCHEMBL7957945 | 0.86 | CNR2 (0.33) | CNR2CYP3A4CYP2D6NFKB1OPRK1 | |
| SCHEMBL7946970 | 0.78 | CNR2 (0.32) | CNR2 | |
| SCHEMBL7954247 | 0.78 | GAA (0.34) | CNR2 | |
| SCHEMBL7955974 | 0.77 | KMT2A (0.37) | — | |
| Water SCHEMBL7954090 | 0.77 | CNR2 (0.32) | CNR2 | |
| SCHEMBL7954235 | 0.77 | TP53 (0.31) | CNR2 | |
| SCHEMBL7954097 | 0.76 | OPRK1 (0.31) | CNR2CYP3A4CYP2D6NFKB1OPRK1 | |
| SCHEMBL7955905 | 0.75 | F10 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271251-B1 | CARDIOVASCULAR DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY LIMITED (JP) | 2001-08-07 | — | — | US | disclosed |
| US-5977100-A | Substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5834454-A | TREATMENT OF ANGINA, ISCHEMIA, ARRHYTHMIA | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0787728-A1 | Substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-08-06 | — | — | EP | disclosed |