Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971430 | 0.90 | OPRD1 (0.53) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL7957961 | 0.89 | OPRD1 (0.52) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL7958158 | 0.88 | OPRD1 (0.57) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL7970900 | 0.88 | OPRD1 (0.52) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL7958178 | 0.86 | OPRD1 (0.57) | OPRD1OPRM1CYP3A4CYP1A2OPRK1 | |
| SCHEMBL6939132 | 0.82 | OPRD1 (0.59) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL6939139 | 0.82 | OPRD1 (0.59) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL4575555 | 0.82 | OPRD1 (0.59) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL7967759 | 0.82 | OPRD1 (0.59) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL6939135 | 0.82 | OPRD1 (0.59) | OPRD1OPRM1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200978-B1 | FOR PREVENTING OR TREATING INFLAMMATORY DISEASES SUCH AS ARTHRITIS, PSORIASIS, ASTHMA, OR INFLAMMATORY BOWEL DISEASE, DISORDERS OF RESPIRATORY FUNCTION, GASTROINTESTINAL DISORDERS SUCH AS FUNCTIONAL BOWEL DISEASE, AS ANALGESICS | PFIZER INC. | 2001-03-13 | — | — | US | disclosed |