Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025587 | 0.94 | KMT2A (0.45) | HPGDKMT2AANPEPATML3MBTL1 | |
| SCHEMBL11061356 | 0.81 | KDM4E (0.43) | HPGDKMT2AANPEPATML3MBTL1 | |
| SCHEMBL11062839 | 0.81 | HPGD (0.46) | HPGDKMT2AANPEPATML3MBTL1 | |
| SCHEMBL26027026 | 0.80 | HPGD (0.40) | HPGDKMT2AANPEPATML3MBTL1 | |
| SCHEMBL11064200 | 0.78 | HPGD (0.44) | HPGDKMT2AANPEPATML3MBTL1 | |
| SCHEMBL11061885 | 0.78 | KDM4E (0.41) | HPGDPKMUSP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL22876904 | 0.78 | ANPEP (0.42) | HPGDKMT2AANPEPATML3MBTL1 | |
| SCHEMBL509597 | 0.78 | — | — | |
| SCHEMBL15671149 | 0.78 | USP2 (0.50) | HPGDKMT2AANPEPATML3MBTL1 | |
| SCHEMBL611743 | 0.77 | KMT2A (0.53) | HPGDKMT2AANPEPATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316464-B1 | P38 MAP kinase inhibitors | SYNTEX (U.S.A.) LLC | 2001-11-13 | — | — | US | disclosed |