Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CDC42 | P60953 | 1/20 | 0.44 |
| ▸ | RAC1 | P63000 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960898 | 0.88 | GPR88 (0.49) | GPR88NPSR1GAAPTGS2KMT2A | |
| SCHEMBL6482521 | 0.84 | NPSR1 (0.47) | GPR88NPSR1PTGS2KMT2APTGS1 | |
| SCHEMBL7960771 | 0.82 | GPR88 (0.53) | GPR88NPSR1GAAPTGS2KMT2A | |
| SCHEMBL7960761 | 0.81 | GPR88 (0.49) | GPR88NPSR1GAAKMT2AOPRM1 | |
| SCHEMBL7961960 | 0.81 | GPR88 (0.49) | GPR88NPSR1GAAPTGS2KMT2A | |
| SCHEMBL7640906 | 0.79 | GPR88 (0.47) | GPR88NPSR1GAAPTGS2KMT2A | |
| SCHEMBL7960866 | 0.79 | SCN1A (0.41) | GPR88PTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL7964623 | 0.77 | GPR88 (0.50) | GPR88NPSR1GAAKMT2AMEN1 | |
| SCHEMBL5741082 | 0.76 | GPR88 (0.55) | GPR88NPSR1GAAPTGS2KMT2A | |
| SCHEMBL7960750 | 0.75 | GPR88 (0.46) | GPR88NPSR1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |