Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2375751 | 0.89 | BACE1 (0.55) | BACE1CTSD | |
| SCHEMBL7964584 | 0.87 | KDM4E (0.35) | BACE1CTSD | |
| SCHEMBL12245437 | 0.82 | BACE1 (0.50) | BACE1CTSD | |
| SCHEMBL2375414 | 0.82 | BACE1 (0.62) | BACE1CTSD | |
| SCHEMBL2376052 | 0.81 | BACE1 (0.53) | BACE1CTSD | |
| SCHEMBL7961006 | 0.80 | BACE1 (0.33) | BACE1CTSD | |
| SCHEMBL2375536 | 0.76 | BACE1 (0.61) | BACE1CTSD | |
| SCHEMBL12245461 | 0.76 | BACE1 (0.49) | BACE1CTSD | |
| SCHEMBL2376169 | 0.76 | BACE1 (0.40) | BACE1CTSD | |
| SCHEMBL2387038 | 0.75 | BACE1 (0.49) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021680-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |