Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960034 | 0.84 | ELANE (0.49) | KMT2AHPGDELANEALDH1A1MAPT | |
| SCHEMBL7950013 | 0.80 | ELANE (0.52) | KMT2AHPGDELANEALDH1A1MAPT | |
| SCHEMBL10463880 | 0.80 | SMN1; SMN2 (0.65) | KMT2AHPGDELANEALDH1A1MAPT | |
| SCHEMBL13013096 | 0.72 | HPGD (0.76) | KMT2AHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL1943035 | 0.71 | HPGD (0.70) | KMT2AHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL11299829 | 0.71 | HPGD (1.00) | KMT2AHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL7950033 | 0.71 | ELANE (0.56) | KMT2AHPGDELANEALDH1A1MAPT | |
| SCHEMBL7960114 | 0.70 | ELANE (0.44) | KMT2AHPGDELANEALDH1A1MAPT | |
| SCHEMBL458844 | 0.70 | GAA (0.60) | KMT2AHPGDELANEALDH1A1MAPT | |
| Methane SCHEMBL3400213 | 0.70 | HPGD (0.97) | KMT2AHPGDALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184245-B1 | Cyclic ketone derivatives and their medical applications | TORAY INDUSTRIES INC. (JP) | 2001-02-06 | — | — | US | disclosed |