Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 12/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958406 | 0.95 | PTGIR (0.56) | PTGIRTBXA2RHTR1AADRA1DADRA1A | |
| SCHEMBL7958938 | 0.89 | PTGIR (0.69) | PTGIRTBXA2RHTR1AADRA1DADRA1A | |
| SCHEMBL7957017 | 0.87 | PTGIR (0.48) | PTGIRTBXA2RPSMB5 | |
| SCHEMBL7958426 | 0.86 | PTGIR (0.47) | PTGIRTBXA2RLTB4RLTB4R2PSMB5 | |
| SCHEMBL7958388 | 0.84 | PTGIR (0.46) | PTGIRTBXA2RPSMB5 | |
| SCHEMBL7960033 | 0.83 | PTGIR (0.64) | PTGIRTBXA2RHTR1AADRA1DADRA1A | |
| SCHEMBL7948961 | 0.82 | PTGIR (0.46) | PTGIRTBXA2RPSMB5 | |
| SCHEMBL7960382 | 0.80 | PTGIR (0.47) | PTGIRTBXA2RPSMB5 | |
| SCHEMBL7958495 | 0.78 | PTGIR (0.59) | PTGIRTBXA2RHTR1AADRA1DADRA1A | |
| SCHEMBL7948871 | 0.78 | PTGIR (0.61) | PTGIRTBXA2RHTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |