Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | CDK4 | P11802 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | CCND1 | P24385 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25753202 | 0.88 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL31186642 | 0.82 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL4532583 | 0.82 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL3642723 | 0.82 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL29531557 | 0.81 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL6698921 | 0.81 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL25229724 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL8703125 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL15921493 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL8435686 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AUSP2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297270-B1 | HERBICIDE; DYES INTERMEDIATE, AMINO ACIDS, PHOTOSENSITIVE AND/OR THERMOSENSITIVE MATERIAL; COSMETICS; ANTIOXIDANT; ANGIOTENSIN(II) ANTAGONIST; CALCIUM CHANNEL BLOCKER, ENZYME INHIBITOR; POLYMERIZATION CATALYST | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2001-10-02 | — | — | US | claimed |
| EP-1004579-A1 | Process for the preparation of 2,3-Dihydroindoles (Indolines), certain 2,3-Dihydroindoles and their use | Aventis Research & Technologies GmbH & Co KG (DE) | 2000-05-31 | — | — | EP | claimed |
| US-6297270-B1 | HERBICIDE; DYES INTERMEDIATE, AMINO ACIDS, PHOTOSENSITIVE AND/OR THERMOSENSITIVE MATERIAL; COSMETICS; ANTIOXIDANT; ANGIOTENSIN(II) ANTAGONIST; CALCIUM CHANNEL BLOCKER, ENZYME INHIBITOR; POLYMERIZATION CATALYST | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2001-10-02 | — | — | US | disclosed |
| EP-1004579-A1 | Process for the preparation of 2,3-Dihydroindoles (Indolines), certain 2,3-Dihydroindoles and their use | Aventis Research & Technologies GmbH & Co KG (DE) | 2000-05-31 | — | — | EP | disclosed |
| EP-1004579-A1 | Process for the preparation of 2,3-Dihydroindoles (Indolines), certain 2,3-Dihydroindoles and their use | Aventis Research & Technologies GmbH & Co KG (DE) | 2000-05-31 | — | — | EP | disclosed |