Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.73 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30682154 | 0.85 | SLC6A4 (1.00) | SLC6A4SOS1SLC6A3SLC6A2 | |
| SCHEMBL930692 | 0.85 | SLC6A4 (1.00) | SLC6A4SOS1SLC6A3SLC6A2 | |
| SCHEMBL7741855 | 0.84 | SLC6A4 (0.71) | SLC6A4SOS1SLC6A3ALDH1A1HSD17B10 | |
| SCHEMBL7735886 | 0.81 | SLC6A4 (0.67) | SLC6A4SOS1SLC6A3ALDH1A1PTGS1 | |
| SCHEMBL3364498 | 0.81 | SLC6A4 (0.67) | SLC6A4SOS1SLC6A3ALDH1A1HSD17B10 | |
| SCHEMBL3363794 | 0.81 | SLC6A4 (0.65) | SLC6A4SOS1ALDH1A1HSD17B10PTGS1 | |
| SCHEMBL7740609 | 0.80 | SLC6A4 (0.82) | SLC6A4SOS1SLC6A3SLC6A2HRH3 | |
| SCHEMBL3362794 | 0.80 | SLC6A4 (0.79) | SLC6A4SOS1SLC6A3SLC6A2HRH3 | |
| SCHEMBL3364730 | 0.80 | SLC6A4 (0.65) | SLC6A4SOS1SLC6A3SLC6A2HRH3 | |
| SCHEMBL7741483 | 0.80 | SLC6A4 (0.65) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8475804-B2 | Compositions and methods for treatment of filovirus-mediated diseases | U.S. ARMY MEDICAL RESEARCH AND MATERIAL COMMAND (US) | 2013-07-02 | — | — | US | disclosed |
| WO-2010021681-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-02-25 | — | — | WO | disclosed |