SCHEMBL7741483

SCHEMBL7741483

CSc1ccc(Oc2ccc(S(N)(=O)=O)cc2C#N)cc1C

nearest known ligand 0.65

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 4/20 0.65
SLC22A12 Q96S37 12/20 0.47
PLA2G7 Q13093 2/20 0.43
EPAS1 Q99814 1/20 0.42
AR P10275 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7741855 0.83 SLC6A4 (0.71) SLC6A4
SCHEMBL3363560 0.82 SCN9A (0.58) SLC22A12PLA2G7
SCHEMBL3364498 0.80 SLC6A4 (0.67) SLC6A4EPAS1
SCHEMBL7735886 0.80 SLC6A4 (0.67) SLC6A4
SCHEMBL7958686 0.80 SLC6A4 (0.73) SLC6A4
SCHEMBL3363794 0.80 SLC6A4 (0.65) SLC6A4
SCHEMBL3361902 0.80 SLC6A4 (0.76) SLC6A4
SCHEMBL30682154 0.79 SLC6A4 (1.00) SLC6A4
SCHEMBL3362794 0.79 SLC6A4 (0.79) SLC6A4
SCHEMBL930692 0.79 SLC6A4 (1.00) SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100009970-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES COMBINATORX (SINGAPORE) PTE. LTD. (SG) 2010-01-14 US disclosed
US-20100009970-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES COMBINATORX (SINGAPORE) PTE. LTD. (SG) 2010-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100009970-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES HTR1A, HTR3B, HTR3A SLC6A4 34/4885SLC22A12 4002/4885PLA2G7 3921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.