Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948970 | 0.86 | AAK1 (0.42) | FPR3FPR2AAK1KDM4ANQO2 | |
| SCHEMBL8800009 | 0.85 | HPGD (0.36) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7960753 | 0.84 | CA12 (0.44) | FPR3FPR2AAK1NQO2IDO1 | |
| SCHEMBL7963434 | 0.81 | AAK1 (0.47) | AAK1NPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL1476859 | 0.80 | AAK1 (0.47) | FPR3FPR2AAK1KDM4ANPC1 | |
| SCHEMBL30751420 | 0.80 | AAK1 (0.47) | FPR3FPR2AAK1KDM4ANPC1 | |
| SCHEMBL8800560 | 0.73 | MGLL (0.38) | — | |
| SCHEMBL244455 | 0.72 | AAK1 (0.43) | FPR3FPR2AAK1IDO1NPC1 | |
| SCHEMBL506329 | 0.72 | AAK1 (0.50) | FPR3FPR2AAK1KDM4A | |
| SCHEMBL28698326 | 0.72 | GAA (0.45) | KDM4ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |