SCHEMBL7958847

SCHEMBL7958847

CN(C)C1CCN(Cc2c(COc3ccc(Cl)cc3)n(C)c3ccccc23)CC1

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPY1R P25929 17/20 0.74
HTR5A P47898 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7956966 0.91 NPY1R (0.74) NPY1R
SCHEMBL7958711 0.89 NPY1R (0.66) NPY1RHTR5A
SCHEMBL7956835 0.89 NPY1R (0.78) NPY1R
SCHEMBL7963481 0.88 NPY1R (0.60) NPY1R
SCHEMBL7963659 0.87 NPY1R (0.59) NPY1R
SCHEMBL7957048 0.87 NPY1R (0.76) NPY1R
SCHEMBL7956883 0.86 NPY1R (0.78) NPY1R
Hydrochloric Acid SCHEMBL7958491 0.85 NPY1R (0.96) NPY1RHTR5A
SCHEMBL7963425 0.85 NPY1R (1.00) NPY1RHTR5A
SCHEMBL7960625 0.85 NPY1R (0.83) NPY1RHTR5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6245761-B1 NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS ELI LILLY AND COMPANY 2001-06-12 US disclosed