SCHEMBL7958968

SCHEMBL7958968

C#CCOCc1cccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP2C9 P11712 1/20 0.44
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
CYP2D6 P10635 1/20 0.42
KMT2A Q03164 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
MEN1 O00255 2/20 0.41
PARP10 Q53GL7 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SLC1A3 P43003 1/20 0.40
SLC1A2 P43004 1/20 0.40
SLC1A1 P43005 1/20 0.40
HPGD P15428 1/20 0.40
HSP90AB1 P08238 1/20 0.40
ACP3 P15309 1/20 0.40
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31012122 0.82 CYP1A2 (0.56) CYP1A2CYP2C19CYP2C9CNR1CNR2
SCHEMBL4850585 0.82 CYP1A2 (0.56) CYP1A2CYP2C19CYP2C9CNR1CNR2
SCHEMBL22876048 0.82 MTNR1A (0.40) NPC1RAB9AHSP90AB1
SCHEMBL6538995 0.82 TDP1 (0.44) CYP1A2CYP2C19CYP2C9CNR1CNR2
SCHEMBL22763160 0.81 CYP2A6 (0.45) CYP1A2KMT2AMEN1TDP1
SCHEMBL22763297 0.79 CYP1A2 (0.43) CYP1A2CYP2C19CYP2D6
SCHEMBL7067038 0.79 CYP1A2 (0.43) CYP1A2CYP2C19CYP2C9CNR1CNR2
SCHEMBL20699461 0.78 KMT2A (0.42) CYP1A2CYP2D6KMT2AMEN1TDP1
SCHEMBL24040032 0.78 MTNR1A (0.40)
SCHEMBL22763099 0.78 CASR (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11080264-A None JP disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
CN-104955332-B The method of preventing and treating arthropod insect 住友化学株式会社 2017-03-29 CN disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
CN-104955332-A Method for controlling arthropod pest SUMITOMO CHEMICAL CO 2015-09-30 CN disclosed
US-6277867-B1 SYNERGISTIC MIXTURES CHINOIN GYOGYSZER ES VEGYESZETI (HU) 2001-08-21 US disclosed
JP-H1180264-A ALLENYLOXYMETHYLNAPHTHALENE, ITS PREPARATION AND POLYMER OBTAINED THEREFROM FUJI OIL CO LTD 1999-03-26 JP disclosed
US-3954793-A INSECTICIDES HENNESSY DOUGLAS J 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 CYP1A2 193/4885CYP2C19 1240/4885CYP2C9 343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.