Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18415560 | 0.86 | MAPT (0.51) | MAPTCYP3A4KDM4EUSP2MAPK1 | |
| SCHEMBL31465685 | 0.85 | CYP3A4 (0.48) | MAPTCYP3A4KDM4EUSP2MAPK1 | |
| SCHEMBL10683659 | 0.84 | HSD17B10 (0.47) | MAPTKDM4ESMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL7959789 | 0.82 | CYP3A4 (0.49) | MAPTCYP3A4KDM4EUSP2MAPK1 | |
| SCHEMBL9641181 | 0.82 | CYP3A4 (0.49) | MAPTCYP3A4KDM4EUSP2MAPK1 | |
| SCHEMBL11271600 | 0.82 | MAPT (0.46) | MAPTKDM4EMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL10676568 | 0.81 | MAPT (0.49) | MAPTCYP3A4KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10677501 | 0.81 | CA12 (0.58) | MAPTKDM4EMAPK1TSHRHSD17B10 | |
| SCHEMBL30977634 | 0.81 | CYP3A4 (0.48) | MAPTCYP3A4KDM4EUSP2MAPK1 | |
| SCHEMBL18415449 | 0.81 | CYP3A4 (0.48) | MAPTCYP3A4KDM4EUSP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3326715-A1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2018-05-30 | — | — | EP | disclosed |
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |