Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25272394 | 0.85 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4EMAPK1GAA | |
| SCHEMBL1282168 | 0.84 | ABCB1 (0.46) | MAPTALDH1A1KDM4EABCB1ABCC1 | |
| SCHEMBL7959792 | 0.82 | MAPT (0.50) | MAPTALDH1A1KDM4EMAPK1GAA | |
| SCHEMBL1286002 | 0.81 | AR (0.44) | MAPTALDH1A1KDM4EMAPK1GAA | |
| SCHEMBL16449128 | 0.81 | NQO2 (0.46) | MAPTALDH1A1KDM4EMAPK1GAA | |
| SCHEMBL19893069 | 0.81 | VCAM1 (0.44) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL3449044 | 0.78 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4EMAPK1GAA | |
| SCHEMBL2848578 | 0.77 | ALDH1A1 (0.47) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL3796800 | 0.75 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4EMAPK1GAA | |
| SCHEMBL1282223 | 0.75 | MAPT (0.50) | MAPTALDH1A1MAPK1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054228-A1 | Process for the preparation of 1-amino 2 or 4 nitro-alkoxy benzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-23 | — | — | EP | disclosed |