Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.48 |
| ▸ | PTGIR | P43119 | 5/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 9/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | RXRG | P48443 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | C5 | P01031 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960373 | 0.89 | PTGIR (0.59) | PTGER4PTGIRPTGER1NR4A2RXRA | |
| SCHEMBL7949757 | 0.84 | PTGIR (0.51) | PTGER4PTGIRPTGER1NR4A2RXRA | |
| SCHEMBL7949669 | 0.81 | PTGIR (0.49) | PTGER4PTGIRPTGER1NR4A2RXRA | |
| SCHEMBL7490977 | 0.80 | FABP4 (0.58) | PTGER4PTGIRPTGER1PTGER3FABP4 | |
| SCHEMBL7493731 | 0.77 | PTGIR (0.44) | PTGER4PTGIRPTGER1RXRARXRB | |
| SCHEMBL7957475 | 0.75 | PTGIR (0.43) | PTGER4PTGIRPTGER1PTGER3FABP4 | |
| SCHEMBL7959978 | 0.74 | PTGER4 (0.71) | PTGER4PTGIRPTGER1NR4A2RXRA | |
| SCHEMBL11527476 | 0.73 | NPC1 (0.61) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL7960451 | 0.73 | PTGER4 (0.81) | PTGER4PTGIRPTGER1NR4A2RXRA | |
| SCHEMBL7957721 | 0.73 | PTGER4 (0.81) | PTGER4PTGIRPTGER1NR4A2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245790-B1 | ANTIINFLAMMATORY AGENTS; GASTROINTESTINAL DISORDERS; SKN DISORDERS; BONE DISORDERS; MUSCLE RELAXANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0989975-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
| WO-1998055468-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-10 | — | — | WO | disclosed |