Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPIN1 | Q9Y657 | 1/20 | 0.57 |
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SCN1A | P35498 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956633 | 0.93 | POLB (0.56) | SPIN1SLC29A1MEN1KMT2ACYP2D6 | |
| SCHEMBL7954379 | 0.90 | SLC29A1 (0.53) | SPIN1SLC29A1MEN1KMT2ACYP2D6 | |
| SCHEMBL7959655 | 0.88 | TSHR (0.60) | SPIN1SLC29A1CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL7953036 | 0.83 | SLC29A1 (0.50) | SLC29A1MEN1KMT2ACYP2D6LMNA | |
| SCHEMBL7953003 | 0.81 | SYK (0.65) | SLC29A1CYP2D6TSHRHTR2BALDH1A1 | |
| SCHEMBL9197339 | 0.75 | SLC29A1 (0.59) | SLC29A1MEN1KMT2ACYP2D6LMNA | |
| SCHEMBL20028142 | 0.75 | EHMT2 (0.67) | SPIN1MEN1KMT2ACYP2D6CYP3A4 | |
| SCHEMBL4036604 | 0.74 | CYP2D6 (0.60) | SPIN1SLC29A1CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL19461978 | 0.74 | SPIN1 (0.57) | SPIN1MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL7954984 | 0.73 | SLC29A1 (0.53) | SPIN1SLC29A1MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297274-B1 | SUBSTITUTED 5-HYDROXYFURANONES | WARNER-LAMBERT COMPANY | 2001-10-02 | — | — | US | claimed |
| WO-1997037985-A1 | NONPEPTIDE ENDOTHELIN ANTAGONISTS WITH INCREASED WATER SOLUBILITY | WARNER-LAMBERT COMPANY (US) | 1997-10-16 | — | — | WO | claimed |
| US-6297274-B1 | SUBSTITUTED 5-HYDROXYFURANONES | WARNER-LAMBERT COMPANY | 2001-10-02 | — | — | US | disclosed |
| WO-1997037985-A1 | NONPEPTIDE ENDOTHELIN ANTAGONISTS WITH INCREASED WATER SOLUBILITY | WARNER-LAMBERT COMPANY (US) | 1997-10-16 | — | — | WO | disclosed |