Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12424124 | 0.80 | KMT2A (0.55) | KMT2AMAPK1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL10645521 | 0.76 | KMT2A (0.54) | ALDH1A1HPGDKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL26259509 | 0.76 | KMT2A (0.62) | KMT2AMAPK1TSHRPIK3CDNPC1 | |
| SCHEMBL26747693 | 0.75 | KMT2A (0.65) | KMT2AMAPK1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL24796270 | 0.73 | KMT2A (0.42) | ALDH1A1KMT2AMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2757944 | 0.73 | KMT2A (0.50) | ALDH1A1KMT2ASMN1; SMN2TSHRPIK3CD | |
| SCHEMBL948885 | 0.72 | KMT2A (0.49) | ALDH1A1HPGDKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9702659 | 0.72 | MAPK1 (0.61) | ALDH1A1HPGDKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL30366355 | 0.72 | MEN1 (0.41) | ALDH1A1HPGDKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL21389134 | 0.71 | KMT2A (0.46) | KMT2AMAPK1TSHRRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265509-B1 | POLYVINYL ACETALS | NOVARTIS AG (CH) | 2001-07-24 | — | — | US | disclosed |
| EP-0807265-B1 | CROSSLINKED POLYMERS | NOVARTIS AG (CH) | 2000-04-12 | — | — | EP | disclosed |
| EP-0807267-B1 | CROSSLINKED POLYMERS CONTAINING URETHANE GROUPS | NOVARTIS AG (CH) | 2000-03-01 | — | — | EP | disclosed |
| US-5932674-A | MOLDING MATERIALS; CONTACT LENSES | NOVARTIS AG (CH) | 1999-08-03 | — | — | US | disclosed |
| US-5807927-A | POLYVINYL ACETALS MODIFIED BY ISOCYANATO ACRYLATES; CONTACT LENSES | CIBA VISION CORPORATION (US) | 1998-09-15 | — | — | US | disclosed |
| EP-0807265-A1 | CROSSLINKED POLYMERS | Novartis AG (CH) | 1997-11-19 | — | — | EP | disclosed |
| EP-0807267-A1 | CROSSLINKED POLYMERS CONTAINING URETHANE GROUPS | Novartis AG (CH) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996024073-A1 | CROSSLINKED POLYMERS CONTAINING URETHANE GROUPS | NOVARTIS AG (CH) | 1996-08-08 | — | — | WO | disclosed |
| WO-1996024074-A1 | CROSSLINKED POLYMERS | NOVARTIS AG (CH) | 1996-08-08 | — | — | WO | disclosed |