Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702275 | 0.85 | MAPK1 (0.62) | MAPK1NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL27418304 | 0.84 | KMT2A (0.51) | MAPK1SMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL2944803 | 0.83 | SMN1; SMN2 (0.50) | MAPK1SMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL29077793 | 0.83 | LMNA (0.54) | MAPK1SMN1; SMN2L3MBTL1TSHRKMT2A | |
| SCHEMBL6359808 | 0.82 | RAB9A (0.60) | MAPK1SMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL19513773 | 0.82 | SMN1; SMN2 (0.49) | MAPK1SMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL21998656 | 0.82 | MAPK1 (0.56) | MAPK1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL21999368 | 0.82 | MAPK1 (0.56) | MAPK1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL21998655 | 0.82 | MAPK1 (0.56) | MAPK1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL10645521 | 0.81 | KMT2A (0.54) | SMN1; SMN2L3MBTL1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118811-A | Treatment and prevention of dementia and amnesia | JAPAN TOBACCO INC. (JP) | 1992-06-02 | — | — | US | disclosed |
| EP-0419683-A1 | NEW AMINO ACID DERIVATIVES HAVING PROLYLENDOPEPTIDASE INHIBITOR ACTIVITY | Japan Tobacco Inc. (JP) | 1991-04-03 | — | — | EP | disclosed |