Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 13/20 | 1.00 |
| ▸ | HTR5A | P47898 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959225 | 0.90 | NPY1R (1.00) | NPY1RHRH3 | |
| SCHEMBL7963425 | 0.90 | NPY1R (1.00) | NPY1RHTR5AHRH3 | |
| Hydrochloric Acid SCHEMBL7956797 | 0.89 | NPY1R (0.98) | NPY1RHTR5AHRH3 | |
| SCHEMBL7960131 | 0.88 | NPY1R (0.79) | NPY1RHRH3 | |
| SCHEMBL7958870 | 0.88 | NPY1R (0.86) | NPY1RHRH3 | |
| Hydrochloric Acid SCHEMBL7958491 | 0.88 | NPY1R (0.96) | NPY1RHTR5AHRH3 | |
| SCHEMBL7956966 | 0.86 | NPY1R (0.74) | NPY1R | |
| SCHEMBL7963653 | 0.84 | NPY1R (0.72) | NPY1R | |
| SCHEMBL7963645 | 0.82 | NPY1R (0.70) | NPY1RHTR5A | |
| SCHEMBL7960625 | 0.81 | NPY1R (0.83) | NPY1RHTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| CN-1173867-A | Indolyl neuropeptide Y receptor antagonists | LILLY CO ELI (US) | 1998-02-18 | — | — | CN | disclosed |
| EP-0789688-A4 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0789688-A1 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1997009308-A1 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |