Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 8/20 | 0.72 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960131 | 0.87 | NPY1R (0.79) | NPY1RSIGMAR1 | |
| SCHEMBL7956966 | 0.85 | NPY1R (0.74) | NPY1R | |
| SCHEMBL7959923 | 0.84 | NPY1R (1.00) | NPY1R | |
| SCHEMBL7959225 | 0.83 | NPY1R (1.00) | NPY1R | |
| SCHEMBL7960764 | 0.82 | DRD4 (0.59) | NPY1RDRD4ALDH1A1 | |
| SCHEMBL7958870 | 0.81 | NPY1R (0.86) | NPY1RTMEM97SIGMAR1 | |
| SCHEMBL7958711 | 0.79 | NPY1R (0.66) | NPY1RSIGMAR1 | |
| Hydrochloric Acid SCHEMBL7960187 | 0.79 | NPY1R (0.80) | NPY1RSIGMAR1ALDH1A1 | |
| SCHEMBL7959104 | 0.78 | NPY1R (0.73) | NPY1RDRD4SLC6A2 | |
| SCHEMBL7956835 | 0.78 | NPY1R (0.78) | NPY1RSIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |