Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.53 |
| ▸ | TUBB | P07437 | 2/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148063 | 0.85 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2TSHRTUBB4A | |
| Methyl Syringate SCHEMBL211747 | 0.85 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2TSHRTUBB4A | |
| SCHEMBL7630712 | 0.84 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2TSHRTUBB4A | |
| SCHEMBL669351 | 0.83 | MEN1 (0.59) | MEN1KMT2ASMN1; SMN2TSHRTUBB4A | |
| SCHEMBL11790985 | 0.82 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2TSHRTUBB4A | |
| SCHEMBL11790977 | 0.82 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2TSHRTUBB4A | |
| SCHEMBL7631406 | 0.81 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2TSHRTUBB4A | |
| SCHEMBL7952964 | 0.81 | SLC29A1 (0.59) | MEN1KMT2ASMN1; SMN2TSHRMAPT | |
| SCHEMBL9311035 | 0.81 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2TSHRTUBB4A | |
| SCHEMBL11332121 | 0.81 | TUBB4A (0.55) | MEN1KMT2ATSHRTUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089926-A2 | Pharmaceutical preparations of tetracycles containing nitrogen, and compounds of this type | CIBA-GEIGY AG (CH) | 1983-09-28 | — | — | EP | claimed |
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |
| US-4393070-A | HYPOTENSIVE, VASODILATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-07-12 | — | — | US | disclosed |
| US-4371534-A | N4-Substituted tetrahydro-1,2,4-oxadiazin-5-one derivatives having anticonvulsive activity and pharmaceutical compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1983-02-01 | — | — | US | disclosed |
| US-4307103-A | TREATMENT OF HYPERTENSION AND CARDIOVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-22 | — | — | US | disclosed |