Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527925 | 0.98 | PRKCA (0.41) | PRKCAMAPTMAPK1TDP1PRKCE | |
| SCHEMBL4836145 | 0.95 | PRKCA (0.40) | PRKCAMAPTMAPK1TDP1PRKCE | |
| SCHEMBL29407006 | 0.85 | PRKCA (0.49) | PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL30531659 | 0.85 | PRKCA (0.49) | PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL10332127 | 0.80 | PRKCA (0.42) | PRKCAMAPTMAPK1PRKCEPRKCQ | |
| SCHEMBL13870383 | 0.78 | MAPT (0.47) | PRKCAMAPTMAPK1PRKCEPRKCQ | |
| SCHEMBL6325341 | 0.78 | USP2 (0.41) | PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL24414625 | 0.78 | TDP1 (0.36) | PRKCAMAPTTDP1TP53 | |
| SCHEMBL24414490 | 0.78 | TDP1 (0.36) | PRKCAMAPTTDP1TP53 | |
| SCHEMBL24414483 | 0.78 | TDP1 (0.36) | PRKCAMAPTTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6260699-B1 | Packaged synthetic absorbable surgical elements | UNITED STATES SURGICAL CORPORATION | 2001-07-17 | — | — | US | disclosed |
| US-5468252-A | Filled suture | UNITED STATES SURGICAL CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |
| US-5462162-A | Packaged synthetic absorbable surgical elements | UNITED STATES SURGICAL CORPORATION (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0471441-B1 | Packaged synthetic absorbable surgical elements | UNITED STATES SURGICAL CORP (US) | 1995-09-27 | — | — | EP | disclosed |
| US-5366081-A | Packaged synthetic absorbable surgical elements | UNITED STATES SURGICAL CORPORATION (US) | 1994-11-22 | — | — | US | disclosed |
| US-5222978-A | Sutures filled with stabilizer | UNITED STATES SURGICAL CORPORATION (US) | 1993-06-29 | — | — | US | disclosed |
| EP-0471441-A1 | Packaged synthetic absorbable surgical elements | United States Surgical Corporation (US) | 1992-02-19 | — | — | EP | disclosed |
| US-5081150-A | Drugs, cosmetics, foods | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-14 | — | — | US | disclosed |