Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957874 | 0.85 | PTGIR (0.56) | PTGIRTBXA2RHPGDSMN1; SMN2GLA | |
| SCHEMBL7956638 | 0.83 | TSHR (0.44) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7960566 | 0.81 | PTGIR (0.66) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7948606 | 0.80 | PTGIR (0.56) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7948782 | 0.80 | PTGIR (0.65) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7958749 | 0.79 | PTGIR (0.55) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7959190 | 0.79 | PTGIR (0.67) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7948850 | 0.78 | TBXA2R (0.46) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7528166 | 0.78 | PTGIR (0.53) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7960287 | 0.78 | PTGIR (0.66) | PTGIRTBXA2RKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |