Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318700 | 0.85 | TSHR (0.52) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL28572048 | 0.81 | LMNA (0.50) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8318696 | 0.79 | TSHR (0.47) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL7960057 | 0.78 | PTGIR (0.58) | PTGIRTBXA2RKDM4ETDP1ALDH1A1 | |
| SCHEMBL11637037 | 0.77 | POLB (0.54) | PTGIRTBXA2RKDM4ETDP1ALDH1A1 | |
| SCHEMBL20509857 | 0.77 | KDM4E (0.54) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL12986383 | 0.76 | L3MBTL1 (0.68) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL7960566 | 0.76 | PTGIR (0.66) | PTGIRTBXA2RKDM4ETDP1ALDH1A1 | |
| SCHEMBL31493900 | 0.76 | TSHR (0.49) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL28731922 | 0.76 | TSHR (0.49) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417213-B2 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-09 | — | — | US | disclosed |
| US-20020006944-A1 | Tricyclic compounds, their production and use | OHKAWA SHIGENORI (JP) | 2002-01-17 | — | — | US | disclosed |
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006944-A1 | Tricyclic compounds, their production and use | CNR1, PTGER1, PTGDR | PTGIR 11/4885TBXA2R 5/4885KDM4E 4000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.