SCHEMBL7960078

SCHEMBL7960078

COC(=O)C1(NC(=O)Cc2ccc(OC)cc2C)CCC(OC)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
ALDH1A1 P00352 3/20 0.42
HPGD P15428 1/20 0.42
APOBEC3A P31941 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42
KDM1A O60341 1/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
WNT3A P56704 1/20 0.36
P2RX7 Q99572 1/20 0.36
CCNE1 P24864 1/20 0.36
CDK2 P24941 1/20 0.36
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
EPHX2 P34913 2/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
SIGMAR1 Q99720 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7960744 0.91 MEN1 (0.42) MEN1KMT2AALDH1A1HPGDAPOBEC3A
SCHEMBL7950115 0.90 ALDH1A1 (0.45) MEN1KMT2AALDH1A1HPGDAPOBEC3A
SCHEMBL6481439 0.88 MEN1 (0.42) MEN1KMT2AALDH1A1P2RX7CCNE1
SCHEMBL7960982 0.88 MEN1 (0.42) MEN1KMT2AALDH1A1HPGDAPOBEC3A
SCHEMBL7958037 0.88 MEN1 (0.42) MEN1KMT2AALDH1A1HPGDAPOBEC3A
SCHEMBL7960737 0.88 KMT2A (0.44) MEN1KMT2AALDH1A1HPGDAPOBEC3A
SCHEMBL7957651 0.87 MEN1 (0.41) MEN1KMT2AALDH1A1HPGDAPOBEC3A
SCHEMBL8653784 0.87 ANO1 (0.42) ALDH1A1HPGDP2RX7SMN1; SMN2
SCHEMBL7964438 0.86 MEN1 (0.46) MEN1KMT2AALDH1A1HPGDAPOBEC3A
SCHEMBL7964653 0.86 MEN1 (0.46) MEN1KMT2AALDH1A1HPGDAPOBEC3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6172255-B1 INSECTICIDES; MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-01-09 US disclosed
US-5830826-A Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides BAYER AKTIENGESELLSCHAFT (DE) 1998-11-03 US disclosed