SCHEMBL79602

SCHEMBL79602

CCCC(=O)CC(=O)NC1CCOC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL136646 1.00
SCHEMBL12341578 1.00
Homoserine Lactone SCHEMBL319044 0.92
SCHEMBL3988875 0.91
SCHEMBL1080050 0.90
SCHEMBL3149044 0.90
SCHEMBL12341644 0.90
Ethyl Acetate SCHEMBL7162873 0.90
SCHEMBL12341575 0.89
SCHEMBL131906 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 372 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4702981-A1 TARGETED ANTIBACTERIAL TREATMENT Københavns Universitet (DK) 2026-03-04 EP claimed
US-20260035729-A1 CREATING A VIBRIO-BASED EDUCATIONAL TOOLSET FOR PROTEIN SIGNALING BIO RAD LABORATORIES INC (US) 2026-02-05 US claimed
CN-119612759-A Method for relieving anaerobic digestion ammonia nitrogen inhibition by using signal molecules and biochar and application thereof 江南大学 2025-03-14 CN claimed
CN-114057284-B Device and method for improving salt impact resistance of anaerobic ammonia oxidation particle system based on quorum sensing 北京工业大学 2024-04-19 CN claimed
US-11944676-B2 Systems and methods for the control of acute hepatopancreatic necrosis disease PEBBLE LABS INC. (US) 2024-04-02 US claimed
CN-117431183-A Salt-tolerant heterotrophic nitrification-aerobic denitrification strain for producing acyl homoserine lactone and application thereof 太原理工大学 2024-01-23 CN claimed
CN-116239711-B Method for removing SBS homogeneous hydrogenation catalyst in SEBS solution 华东理工大学 2023-09-12 CN claimed
CN-116239711-A Method for removing SBS homogeneous hydrogenation catalyst in SEBS solution 华东理工大学 2023-06-09 CN claimed
CN-113122553-B N-acyl homoserine lactone acyltransferase encoding gene aigA and application thereof 华南农业大学 2023-03-31 CN claimed
CN-113106111-B N-acyl homoserine lactone acyltransferase encoding gene aigC and application thereof 华南农业大学 2023-03-31 CN claimed
US-20230038480-A1 SYSTEM FOR PRODUCITON OF HIGH YIELD OF RECOMBINANT PROTEINS UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2023-02-09 US claimed
US-20220304313-A1 METHODS FOR DEGRADING AHL SIGNALING MOLECULES OR PREVENTING PLANT DISEASE CAUSED THEREBY SOUTH CHINA AGRICULTURAL UNIVERSITY (CN) 2022-09-29 US claimed
CN-112986420-B Method for detecting microbial aggregate quorum sensing effect molecules by UPLC-MS/MS method 军事科学院军事医学研究院环境医学与作业医学研究所 2022-09-13 CN claimed
CN-113322269-B Biosensor based on bacterial population density sensing protein LuxR and application thereof 中国人民解放军军事科学院军事医学研究院 2022-08-09 CN claimed
CN-114057284-A Device and method for improving salt impact resistance of anaerobic ammonia oxidation particle system based on quorum sensing effect 北京工业大学 2022-02-18 CN claimed
EP-0994961-B1 HOMOSERINE LACTONES BIOFILM REGULATING COMPOUNDS AND THEIR METHODS OF USE UNIV MONTANA STATE (US) 2006-10-18 EP claimed
EP-0994961-A4 HOMOSERINE LACTONES BIOFILM REGULATING COMPOUNDS AND THEIR METHODS OF USE UNIV MONTANA RES DEV INST (US) 2003-01-15 EP claimed
EP-0994961-A2 HOMOSERINE LACTONES BIOFILM REGULATING COMPOUNDS AND THEIR METHODS OF USE The Research and development Institute, Inc (US) 2000-04-26 EP claimed
WO-1998058075-A2 HOMOSERINE LACTONES BIOFILM REGULATING COMPOUNDS AND THEIR METHODS OF USE THE RESEARCH AND DEVELOPMENT INSTITUTE, INC. (US) 1998-12-23 WO claimed
US-12595468-B2 Transcriptional recording by CRISPR spacer acquisition from RNA ETH Zürich (CH) 2026-04-07 US disclosed
US-12571789-B1 Microbial subsurface soil sensors RTX BBN TECHNOLOGIES, INC. (US) 2026-03-10 US disclosed
EP-4702981-A1 TARGETED ANTIBACTERIAL TREATMENT Københavns Universitet (DK) 2026-03-04 EP disclosed
US-12565474-B2 Discovery, total synthesis, and bioactivity of doscadenamides UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2026-03-03 US disclosed
US-20260035729-A1 CREATING A VIBRIO-BASED EDUCATIONAL TOOLSET FOR PROTEIN SIGNALING BIO RAD LABORATORIES INC (US) 2026-02-05 US disclosed
EP-3833366-B1 MICROORGANISM MIXTURES, MOLECULES DERIVED THEREFROM, AND METHODS OF USE THEREOF B G NEGEV TECHNOLOGIES AND APPLICATIONS LTD AT BEN GURION UNIV (IL) 2025-12-03 EP disclosed
US-20250352625-A1 METHODS AND COMPOSITIONS FOR METHIONINE RESTRICTION PETRI BIO, INC. (US) 2025-11-20 US disclosed
EP-4584280-A1 MATERIALS AND METHODS TO PRODUCE INSECTICIDAL TOXINS Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-07-16 EP disclosed
US-20250223544-A1 SYNTHETIC QUORUM-REGULATED LYSIS UNIV CALIFORNIA (US) 2025-07-10 US disclosed
EP-2925139-B1 FERMENTED SOIL ADDITIVE LIQUID FERTILISER SYSTEMS PTY LTD (AU) 2025-04-30 EP disclosed
CN-119804714-A LC-MSMS-based method for quantifying anaerobic fermentation substances and AHLs in activated sludge 农业农村部成都沼气科学研究所 2025-04-11 CN disclosed
EP-4531881-A2 METHODS AND COMPOSITIONS FOR METHIONINE RESTRICTION Petri Bio, Inc. (US) 2025-04-09 EP disclosed
CN-119612759-A Method for relieving anaerobic digestion ammonia nitrogen inhibition by using signal molecules and biochar and application thereof 江南大学 2025-03-14 CN disclosed
CN-119612759-A Method for relieving anaerobic digestion ammonia nitrogen inhibition by using signal molecules and biochar and application thereof 江南大学 2025-03-14 CN disclosed
US-20250058002-A1 ELECTROCHEMICAL INHIBITION OF REDOX ACTIVE BACTERIA AND RELATED DEVICES, METHODS AND SYSTEMS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2025-02-20 US disclosed
US-12209256-B2 System for protein inactivation and recombinant phages for targeted bacterial killing, infection, biodetection, and as a means of protein extraction THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-01-28 US disclosed
US-12191002-B2 Dynamic characterization of synthetic genetic circuits in living cells MICROSOFT TECHNOLOGY LICENSING, LLC (US) 2025-01-07 US disclosed
CN-119157148-A Application of quorum sensing quenching enzyme in pathogenic control of vibrio coralloides 华侨大学 2024-12-20 CN disclosed
EP-3815088-B1 DYNAMIC CHARACTERIZATION OF SYNTHETIC GENETIC CIRCUITS IN LIVING CELLS MICROSOFT TECHNOLOGY LICENSING LLC (US) 2024-07-24 EP disclosed
CN-118240913-A Quorum sensing quenching enzyme and screening method and application thereof 深圳先进技术研究院 2024-06-25 CN disclosed
CN-112703249-B Transcription recording by CRISPR spacer sequences obtained from RNA 苏黎世联邦理工学院 2024-05-17 CN disclosed
CN-117925676-A Modularized orthogonal eukaryotic transcription factor model construction method 中国科学院深圳先进技术研究院 2024-04-26 CN disclosed
CN-114057284-B Device and method for improving salt impact resistance of anaerobic ammonia oxidation particle system based on quorum sensing 北京工业大学 2024-04-19 CN disclosed
CN-114057284-B Device and method for improving salt impact resistance of anaerobic ammonia oxidation particle system based on quorum sensing 北京工业大学 2024-04-19 CN disclosed
US-11944676-B2 Systems and methods for the control of acute hepatopancreatic necrosis disease PEBBLE LABS INC. (US) 2024-04-02 US disclosed
WO-2024052546-A1 MATERIALS AND METHODS TO PRODUCE INSECTICIDAL TOXINS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2024-03-14 WO disclosed
EP-4335866-A1 MATERIALS AND METHODS TO PRODUCE INSECTICIDAL TOXINS Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2024-03-13 EP disclosed
CN-117431183-A Salt-tolerant heterotrophic nitrification-aerobic denitrification strain for producing acyl homoserine lactone and application thereof 太原理工大学 2024-01-23 CN disclosed
WO-2023235846-A2 METHODS AND COMPOSITIONS FOR METHIONINE RESTRICTION PETRI BIO, INC. (US) 2023-12-07 WO disclosed
CN-112694170-B Method and device for improving anaerobic ammonia oxidation denitrification effect and operation stability at low temperature 北京工业大学 2023-11-17 CN disclosed
CN-116239711-B Method for removing SBS homogeneous hydrogenation catalyst in SEBS solution 华东理工大学 2023-09-12 CN disclosed
US-20230282303-A1 DYNAMIC CHARACTERIZATION OF SYNTHETIC GENETIC CIRCUITS IN LIVING CELLS MICROSOFT TECHNOLOGY LICENSING, LLC 2023-09-07 US disclosed
US-20230242482-A9 DISCOVERY, TOTAL SYNTHESIS, AND BIOACTIVITY OF DOSCADENAMIDES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-08-03 US disclosed
US-20230240305-A1 STABILIZED MUTANTS OF QUORUM QUENCHING LACTONASE AND USE THEREOF IN TREATMENT OF PATHOGENS MIGAL GALILEE RESEARCH INSTITUTE LTD. (IL) 2023-08-03 US disclosed
US-20230225332-A1 COMPOSITIONS COMPRISING AROMATIC DIPEPTIDES-BASED STRUCTURES ENCAPSULATING AN ESTERASE AND USES THEREOF MIGAL GALILEE RES INSTITUTE LTD (IL) 2023-07-20 US disclosed
US-11694766-B2 Dynamic characterization of synthetic genetic circuits in living cells MICROSOFT TECHNOLOGY LICENSING, LLC (US) 2023-07-04 US disclosed
CN-116239711-A Method for removing SBS homogeneous hydrogenation catalyst in SEBS solution 华东理工大学 2023-06-09 CN disclosed
CN-114634891-B Bacillus bailii ZH3 and application thereof 厦门萤星海科技有限公司 2023-06-02 CN disclosed
EP-4167745-A1 COMPOSITIONS COMPRISING AROMATIC DIPEPTIDES-BASED STRUCTURES ENCAPSULATING AN ESTERASE AND USES THEREOF Migal Galilee Research Institute Ltd. (IL) 2023-04-26 EP disclosed
CN-112961847-B Application of Bacillus belgii YtnP-homologous lactonase in oral cavity department hygiene disinfection 华侨大学 2023-03-31 CN disclosed
CN-113122553-B N-acyl homoserine lactone acyltransferase encoding gene aigA and application thereof 华南农业大学 2023-03-31 CN disclosed
CN-113106111-B N-acyl homoserine lactone acyltransferase encoding gene aigC and application thereof 华南农业大学 2023-03-31 CN disclosed
US-20230038480-A1 SYSTEM FOR PRODUCITON OF HIGH YIELD OF RECOMBINANT PROTEINS UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2023-02-09 US disclosed
US-20230038480-A1 SYSTEM FOR PRODUCITON OF HIGH YIELD OF RECOMBINANT PROTEINS UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2023-02-09 US disclosed
US-20220411390-A1 MODULATION OF BACTERIAL QUORUM SENSING WITH SYNTHETIC LIGANDS WISCONSIN ALUMNI RES FOUND (US) 2022-12-29 US disclosed
US-20220403419-A1 CRISPR-BASED METHODS FOR RECORDING BIOLOGICAL SIGNALS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2022-12-22 US disclosed
US-11473153-B2 Device and methods of using device for separation of bacteria from complex samples UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2022-10-18 US disclosed
US-20220304313-A1 METHODS FOR DEGRADING AHL SIGNALING MOLECULES OR PREVENTING PLANT DISEASE CAUSED THEREBY SOUTH CHINA AGRICULTURAL UNIVERSITY (CN) 2022-09-29 US disclosed
CN-112986420-B Method for detecting microbial aggregate quorum sensing effect molecules by UPLC-MS/MS method 军事科学院军事医学研究院环境医学与作业医学研究所 2022-09-13 CN disclosed
US-20220281816-A1 DISCOVERY, TOTAL SYNTHESIS, AND BIOACTIVITY OF DOSCADENAMIDES University of Florida Research Foundation, Incorporation (US) 2022-09-08 US disclosed
CN-113322269-B Biosensor based on bacterial population density sensing protein LuxR and application thereof 中国人民解放军军事科学院军事医学研究院 2022-08-09 CN disclosed
CN-113322269-B Biosensor based on bacterial population density sensing protein LuxR and application thereof 中国人民解放军军事科学院军事医学研究院 2022-08-09 CN disclosed
CN-114634891-A Bacillus belgii ZH3 and application thereof 厦门萤星海科技有限公司 2022-06-17 CN disclosed
US-11357786-B2 Synthetic disugar hydrocarbons as natural analogs to control microbial behaviors SYRACUSE UNIVERSITY (US) 2022-06-14 US disclosed
CN-114145303-B Application of benzothiazole compound in preparation of agrobacterium tumefaciens quorum sensing inhibitor 华南农业大学 2022-05-31 CN disclosed
US-20220160680-A1 MICROORGANISM MIXTURES, MOLECULES DERIVED THEREFROM, AND METHODS OF USE THEREOF B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) 2022-05-26 US disclosed
US-20220154156-A1 PROTEINS AND METHODS FOR DISRUPTING BACTERIAL COMMUNICATION REGENTS OF THE UNIVERSITY OF MINNESOTA 2022-05-19 US disclosed
EP-3983535-A1 STABILIZED MUTANTS OF QUORUM QUENCHING LACTONASE AND USE THEREOF IN TREATMENT OF PATHOGENS Migal Galilee Research Institute Ltd. (IL) 2022-04-20 EP disclosed
CN-114302959-A Stable mutants of quorum sensing quenched lactonases and their use in the treatment of pathogens 米加尔-加利里研究院有限公司 2022-04-08 CN disclosed
CN-114145303-A Application of benzothiazole compound in preparation of agrobacterium tumefaciens quorum sensing inhibitor 华南农业大学 2022-03-08 CN disclosed
CN-112043697-B Application of benzothiazole compound as quorum sensing inhibitor in treatment of bacterial diseases 华南农业大学 2022-02-22 CN disclosed
CN-114057284-A Device and method for improving salt impact resistance of anaerobic ammonia oxidation particle system based on quorum sensing effect 北京工业大学 2022-02-18 CN disclosed
CN-114057284-A Device and method for improving salt impact resistance of anaerobic ammonia oxidation particle system based on quorum sensing effect 北京工业大学 2022-02-18 CN disclosed
CN-112042648-B Methyl cinnamate as quorum sensing inhibitor and application thereof in treating bacterial diseases 华南农业大学 2022-01-25 CN disclosed
US-20210023108-A1 SYNTHETIC DISUGAR HYDROCARBONS AS NATURAL ANALOGS TO CONTROL MICROBIAL BEHAVIORS SYRACUSE UNIVERSITY (US) 2021-01-28 US disclosed
US-10702497-B2 Use of acyl-homoserine lactone derivatives as anti-thrombotic agents THE UNIVERSITY OF TOLEDO (US) 2020-07-07 US disclosed
US-20190282597-A1 SYNTHETIC DISUGAR HYDROCARBONS AS NATURAL ANALOGS TO CONTROL MICROBIAL BEHAVIORS SYRACUSE UNIVERSITY (US) 2019-09-19 US disclosed
US-20190111023-A1 USE OF ACYL-HOMOSERINE LACTONE DERIVATIVES AS ANTI-THROMBOTIC AGENTS THE UNIVERSITY OF TOLEDO (US) 2019-04-18 US disclosed
EP-2311849-B1 Specific binding agents of human angiopoietin-2 AMGEN INC (US) 2017-08-16 EP disclosed
CN-107012109-A Applications of the signaling molecule C6 AHL in Phage Infection Escherichia coli are suppressed 昆明理工大学 2017-08-04 CN disclosed
US-20170014437-A1 SYNTHETIC DISUGAR HYDROCARBONS AS NATURAL ANALOGS TO CONTROL MICROBIAL BEHAVIORS SYRACUSE UNIVERSITY (US) 2017-01-19 US disclosed
US-9534032-B2 Thrombopoietic compounds AMGEN INC. (US) 2017-01-03 US disclosed
US-20160176926-A1 PEPTIDES AND RELATED MOLECULES THAT BIND TO TALL-1 AMGEN INC (US) 2016-06-23 US disclosed
CN-105530949-A Myostatin antagonism in human subjects AMGEN INC 2016-04-27 CN disclosed
US-20160038588-A1 Myostatin Antagonism in Human Subjects AMGEN INC (US) 2016-02-11 US disclosed
EP-2968463-A1 MYOSTATIN ANTAGONISM IN HUMAN SUBJECTS Amgen Inc. (US) 2016-01-20 EP disclosed
US-9200040-B2 Specific binding agents of human angiopoietin-2 AMGEN INC. (US) 2015-12-01 US disclosed
WO-2015153961-A1 SYNTHETIC DISUGAR HYDROCARBONS AS NATURAL ANALOGOS TO CONTROL MICROBIAL BEHAVIORS LUK YAN-YEUNG (US) 2015-10-08 WO disclosed
US-9145450-B2 Thrombopoietic compounds AMGEN INC. (US) 2015-09-29 US disclosed
US-9139645-B2 Peptides and related molecules that bind to TALL-1 AMGEN INC. (US) 2015-09-22 US disclosed
US-20150175687-A1 MYOSTATIN BINDING AGENTS AMGEN INC. 2015-06-25 US disclosed
EP-2845864-A2 Peptides and related molecules that bind to TALL - 1 Amgen, Inc (US) 2015-03-11 EP disclosed
US-20150024431-A1 THROMBOPOIETIC COMPOUNDS AMGEN INC. (US) 2015-01-22 US disclosed
US-8920798-B2 Myostatin binding agents, nucleic acids encoding the same, and methods of treatment AMGEN INC. (US) 2014-12-30 US disclosed
EP-1921088-B1 Peptides and related molecules that bind to tall-1 AMGEN INC (US) 2014-10-08 EP disclosed
US-20140294866-A1 Uses of Myostatin Antagonists AMGEN INC. 2014-10-02 US disclosed
US-20140275479-A1 SPECIFIC BINDING AGENTS OF HUMAN ANGIOPOEITIN-2 AMGEN INC. (US) 2014-09-18 US disclosed
WO-2014144903-A1 MYOSTATIN ANTAGONISM IN HUMAN SUBJECTS AMGEN INC. (US) 2014-09-18 WO disclosed
US-20140234334-A1 PEPTIDES AND RELATED MOLECULES THAT BIND TO TALL-1 AMGEN INC. (US) 2014-08-21 US disclosed
US-20140234945-A1 TRANSTHYRETIN VARIANTS AMGEN INC. (US) 2014-08-21 US disclosed
US-20140221210-A1 ACYL-HOMOSERINE LACTONE DERIVATIVES FOR IMPROVING PLANT YIELD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-08-07 US disclosed
US-20140221210-A1 ACYL-HOMOSERINE LACTONE DERIVATIVES FOR IMPROVING PLANT YIELD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-08-07 US disclosed
US-8748571-B2 Thrombopoietic compounds AMGEN INC. (US) 2014-06-10 US disclosed
EP-2319928-B9 Dimeric thrombopoietin peptide mimetics binding to MP1 receptor and having thrombopoietic activity KIRIN AMGEN INC (US) 2014-04-16 EP disclosed
US-8663927-B2 Systems and methods for diagnosis and monitoring of bacteria-related conditions UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2014-03-04 US disclosed
US-8633153-B2 Transthyretin variants AMGEN INC. (US) 2014-01-21 US disclosed
EP-2679235-A2 Peptides and related molecules that modulate nerve growth factor activity Amgen Inc. (US) 2014-01-01 EP disclosed
US-8618044-B2 Thrombopoietic compounds AMGEN INC. (US) 2013-12-31 US disclosed
US-20130316448-A1 PEPTIDES AND RELATED MOLECULES THAT MODULATE NERVE GROWTH FACTOR ACTIVITY AMGEN INC. (US) 2013-11-28 US disclosed
EP-2666473-A1 Peptides and related molecules that modulate nerve growth factor activity AMGEN INC. (US) 2013-11-27 EP disclosed
EP-2666474-A1 Peptides and related molecules that modulate nerve growth factor activity Amgen Inc. (US) 2013-11-27 EP disclosed
US-20130230515-A1 MYOSTATIN BINDING AGENTS AMGEN INC. (US) 2013-09-05 US disclosed
US-8513396-B2 Peptides and related molecules that modulate nerve growth factor activity AMGEN INC. (US) 2013-08-20 US disclosed
US-8507426-B2 Peptides and related molecules that bind to TALL-1 AMGEN, INC. (US) 2013-08-13 US disclosed
US-20130158234-A1 SPECIFIC BINDING AGENTS OF HUMAN ANGIOPOIETIN-2 AMGEN INC. (US) 2013-06-20 US disclosed
EP-1439852-B1 PEPTIDES AND RELATED COMPOUNDS HAVING THROMBOPOIETIC ACTIVITY AMGEN INC (US) 2013-05-29 EP disclosed
EP-2319928-B1 Dimeric thrombopoietin peptide mimetics binding to MP1 receptor and having thrombopoietic activity KIRIN AMGEN INC (US) 2013-03-27 EP disclosed
WO-2013034621-A1 ACYL-HOMOSERINE LACTONE DERIVATIVES FOR IMPROVING PLANT YIELD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-03-14 WO disclosed
EP-2316845-B1 Specific binding agents of human angiopoietin-2 AMGEN INC (US) 2013-01-16 EP disclosed
EP-1496926-B1 USE OF TRANSTHYRETIN PEPTIDE/PROTEIN FUSIONS TO INCREASE THE SERUM HALF-LIFE OF PHARMACOLOGICALLY ACTIVE PEPTIDES/PROTEINS AMGEN INC (US) 2012-12-19 EP disclosed
EP-1144454-B2 MODIFIED PEPTIDES AS THERAPEUTIC AGENTS AMGEN INC (US) 2012-12-12 EP disclosed
EP-1545581-B1 Peptides that modulate nerve growth factor (NGF) activity, their compositions and use AMGEN INC (US) 2012-10-24 EP disclosed
EP-2070944-B1 Specific binding agents of human angiopoietin-2 AMGEN INC (US) 2012-09-26 EP disclosed
US-8269024-B2 Compounds and methods for modulating communication and virulence in quorum sensing bacteria WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-09-18 US disclosed
US-8269024-B2 Compounds and methods for modulating communication and virulence in quorum sensing bacteria WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-09-18 US disclosed
US-20120208760-A1 THROMBOPOIETIC COMPOUNDS AMGEN INC. (US) 2012-08-16 US disclosed
US-20120141499-A1 SPECIFIC BINDING AGENTS OF HUMAN ANGIOPOIETIN-2 OLINER JONATHAN DANIEL (US) 2012-06-07 US disclosed
EP-1783222-B1 Dimeric thrombopoietin peptide mimetics binding to MPL receptor and having thrombopoietic activity. KIRIN AMGEN INC (US) 2012-06-06 EP disclosed
US-20120129771-A1 PEPTIDES AND RELATED MOLECULES THAT MODULATE NERVE GROWTH FACTOR ACTIVITY AMGEN INC. (US) 2012-05-24 US disclosed
US-20120083442-A1 MYOSTATIN BINDING AGENTS AMGEN INC. (US) 2012-04-05 US disclosed
EP-2292655-B1 Peptides and related molecules that bind to tall-1 AMGEN INC (US) 2012-03-14 EP disclosed
US-8129331-B2 Specific binding agents of human angiopoietin-2 AMGEN INC. (US) 2012-03-06 US disclosed
US-8124724-B2 Peptides and related molecules that modulate nerve growth factor activity AMGEN INC. (US) 2012-02-28 US disclosed
US-20120034657-A1 THROMBOPOIETIC COMPOUNDS AMGEN INC. (US) 2012-02-09 US disclosed
US-8071538-B2 Method of increasing muscle mass by administering a myostatin binding agent AMGEN INC. 2011-12-06 US disclosed
EP-1615952-B1 METHODS OF TREATMENT OF INFLAMMATORY DISEASES USING SPECIFIC BINDING AGENTS OF HUMAN ANGIOPOIETIN-2 AMGEN INC (US) 2011-11-02 EP disclosed
US-8044174-B2 Peptides and polypeptides which may be used to increase platelets or platelet precursors (e.g., megakaryocytes) in a mammal AMGEN INC. (US) 2011-10-25 US disclosed
US-20110229472-A1 Peptides and Related Compounds Having Thrombopoietic Activity AMGEN INC. (US) 2011-09-22 US disclosed
US-7994117-B2 Thrombopoietic compounds AMGEN INC. (US) 2011-08-09 US disclosed
EP-2332974-A2 Osteoprotegerin Amgen, Inc (US) 2011-06-15 EP disclosed
EP-2319928-A1 Dimeric thrombopoietin peptide mimetics binding to MP1 receptor and having thrombopoietic activity Kirin-Amgen, Inc. (US) 2011-05-11 EP disclosed
EP-2316845-A1 Specific binding agents of human angiopoietin-2 Amgen Inc. (US) 2011-05-04 EP disclosed
EP-2311849-A1 Specific binding agents of human angiopoietin-2 Amgen, Inc (US) 2011-04-20 EP disclosed
US-7928074-B2 Using interleukin-1 specfic immunoglobulin fusion and tumor necrosis factor inhibitors to treat inflammatory and/or autoimmune disorders AMGEN INC. (US) 2011-04-19 US disclosed
US-7928075-B2 Binding agents which inhibit myostatin AMGEN INC. (US) 2011-04-19 US disclosed
US-20110071077-A1 Thrombopoietic Compounds AMGEN INC. (US) 2011-03-24 US disclosed
EP-2298331-A2 Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins Amgen, Inc (US) 2011-03-23 EP disclosed
EP-2292655-A1 Peptides and related molecules that bind to tall-1 Amgen SF, LLC (US) 2011-03-09 EP disclosed
EP-1581649-B1 BINDING AGENTS WHICH INHIBIT MYOSTATIN AMGEN INC (US) 2011-01-26 EP disclosed
US-20110008375-A1 Uses of Myostatin Antagonists AMGEN INC. 2011-01-13 US disclosed
EP-2272864-A2 Binding agents which inhibit myostatin AMGEN INC. (US) 2011-01-12 EP disclosed
US-20100330072-A1 Myostatin binding agents AMGEN INC. (US) 2010-12-30 US disclosed
US-20100305182-A1 COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA BLACKWELL HELEN E 2010-12-02 US disclosed
US-20100305182-A1 COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA BLACKWELL HELEN E 2010-12-02 US disclosed
US-20100298229-A1 OSTEOPROTEGERIN AMGEN INC. 2010-11-25 US disclosed
US-20100291566-A1 SYSTEMS AND METHODS FOR DIAGNOSIS AND MONITORING OF BACTERIA-RELATED CONDITIONS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2010-11-18 US disclosed
US-20100286060-A1 SPECIFIC BINDING AGENTS OF HUMAN ANGIOPOEITIN-2 AMGEN INC. (US) 2010-11-11 US disclosed
US-7803923-B2 Growth differentiation factor-8 binding agents for treatment of metabolic, nervous system, muscular, bone , urogenital and inflammatory disorders; for treating muscle-wasting disorders and metabolic disorders including diabetes and obesity AMGEN INC. (US) 2010-09-28 US disclosed
US-20100240590-A1 PEPTIDES AND RELATED MOLECULES THAT BIND TO TALL-1 AMGEN INC. 2010-09-23 US disclosed
US-20100240582-A1 Peptides and related molecules that modulate nerve growth factor activity AMGEN INC. 2010-09-23 US disclosed
US-7790674-B2 Methods of treatment using specific binding agents of human angiopoietin-2 AMGEN INC. (US) 2010-09-07 US disclosed
US-20100216835-A1 Method For Modulating Microbial Quorum Sensing HANDELSMAN JO E 2010-08-26 US disclosed
US-7771965-B2 Tumor endothelial marker 5α molecules and uses thereof AMGEN INC. (US) 2010-08-10 US disclosed
EP-1124961-B9 THROMBOPOIETIC COMPOUNDS KIRIN AMGEN INC (US) 2010-07-21 EP disclosed
US-7737111-B2 Tumor necrosis factors; cytokines; immunoglobulins; autoimmune diseases AMGEN, INC. (US) 2010-06-15 US disclosed
US-7723499-B2 polynucleotides that code for polypeptides comprising amino acid sequences that preferentially recognize and bind to angiopoietins AMGEN INC. (US) 2010-05-25 US disclosed
EP-2157097-A1 Specific binding agents of human angiopoietin-2 Amgen, Inc. (US) 2010-02-24 EP disclosed
US-7666839-B2 Administering peptibodies, i.e., peptides fused to other molecules such as an Fc domain of an antibody, where the peptide moiety specifically binds to Ang-2 ( angiopoietin-2); antiinflammatory agent; antirheumatic agent AMGEN INC. (US) 2010-02-23 US disclosed
US-7666831-B2 Administering peptibodies, i.e., peptides fused to other molecules such as an Fc domain of an antibody, where the peptide moiety specifically binds to Ang-2 ( angiopoietin-2); antiinflammatory agent; antirheumatic agent AMGEN INC. (US) 2010-02-23 US disclosed
US-7666832-B2 Administering peptibodies, i.e., peptides fused to other molecules such as an Fc domain of an antibody, where the peptide moiety specifically binds to Ang-2 ( angiopoietin-2); antiinflammatory agent; antirheumatic agent AMGEN INC. (US) 2010-02-23 US disclosed
US-7642285-B2 Compounds and methods for modulating communication and virulence in quorum sensing bacteria WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-01-05 US disclosed
US-7642285-B2 Compounds and methods for modulating communication and virulence in quorum sensing bacteria WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-01-05 US disclosed
US-7632922-B1 Osteoprotegerin AMGEN, INC. (US) 2009-12-15 US disclosed
EP-1434791-B1 SPECIFIC BINDING AGENTS OF HUMAN ANGIOPOIETIN-2 AMGEN INC (US) 2009-10-07 EP disclosed
US-20090227517-A1 Growth differentiation factor-8 binding agents for treatment of metabolic, nervous system, muscular, bone , urogenital and inflammatory disorders; for treating muscle-wasting disorders and metabolic disorders including diabetes and obesity AMGEN INC. (US) 2009-09-10 US disclosed
US-20090220491-A1 Binding agents which inhibit myostatin AMGEN INC. (US) 2009-09-03 US disclosed
US-7579316-B2 Administering CTLA-4, tumor necrosis factor inhibitors, and immunogens AMGEN INC. (US) 2009-08-25 US disclosed
EP-1385882-B9 PEPTIDES AND RELATED MOLECULES THAT BIND TO TALL-1 AMGEN INC (US) 2009-08-12 EP disclosed
US-20090191624-A1 Use of transthyretin peptide/protein fussions to increase the serum half-life of pharmacologically active peptides/proteins AMGEN INC. (US) 2009-07-30 US disclosed
US-20090186822-A1 Thrombopoietic Compounds AMGEN INC. (US) 2009-07-23 US disclosed
EP-1684791-A4 COMPOSITIONS AND METHODS TO MODULATE AN IMMUNE RESPONSE TO AN IMMUNOGENIC THERAPEUTIC AGENT AMGEN INC (US) 2009-07-01 EP disclosed
EP-2070944-A1 Specific binding agents of human angiopoietin-2 Amgen Inc. (US) 2009-06-17 EP disclosed
US-7511012-B2 Growth differentiation factor -8 binding agents for treatment of metabolic, nervous system, muscular, bone , urogenital and inflammatory disorders AMGEN INC. (US) 2009-03-31 US disclosed
US-20090054323-A1 Ang-2 inhibitor peptides; use treating tumors, eye disorders, bone disorders, psoriasis; angiogenesis inhibitors; amino acid sequence WDPWT AMGEN INC. (US) 2009-02-26 US disclosed
US-20090053242-A1 Thrombopoietic compounds AMGEN INC. (US) 2009-02-26 US disclosed
US-7488590-B2 Fusion of Fc domains with biologically active peptides; selecting peptide that modulates the activity of AGP-3, preparing a gene construct; expressing the pharmacologically active compound in which an Fc domain is covalently linked to peptide AMGEN INC. (US) 2009-02-10 US disclosed
US-20090011497-A1 Peptides and related compounds having thrombopoietic activity AMGEN INC. 2009-01-08 US disclosed
US-20080279862-A1 Combination Therapy with Co-Stimulatory Factors AMGEN INC. 2008-11-13 US disclosed
EP-1990415-A1 Osteoprotegerin Amgen Inc. (US) 2008-11-12 EP disclosed
EP-1986677-A2 THROMBOPOIETIC COMPOUNDS Amgen Inc. (US) 2008-11-05 EP disclosed
EP-1581649-A4 BINDING AGENTS WHICH INHIBIT MYOSTATIN AMGEN INC (US) 2008-10-08 EP disclosed
EP-0784093-B1 Osteoprotegerin AMGEN INC (US) 2008-10-01 EP disclosed
EP-1968621-A2 USES OF MYOSTATIN ANTAGONISTS Amgen Inc. (US) 2008-09-17 EP disclosed
WO-2008087454-A2 POLYMER INHIBITORS OF QUORUM SENSING UNIVERSITY OF KENT (GB) 2008-07-24 WO disclosed
US-7384639-B2 Methods of treating or preventing an infectious disease using an immunogenic conjugate of a gram-negative bacterial autoinducer molecule UNIVERSITY OF ROCHESTER (US) 2008-06-10 US disclosed
US-7384639-B2 Methods of treating or preventing an infectious disease using an immunogenic conjugate of a gram-negative bacterial autoinducer molecule UNIVERSITY OF ROCHESTER (US) 2008-06-10 US disclosed
EP-1921088-A2 Peptides and related molecules that bind to tall-1 Amgen Inc. (US) 2008-05-14 EP disclosed
US-7371559-B2 Peptides and related molecules that modulate nerve growth factor activity AMGEN INC. (US) 2008-05-13 US disclosed
CN-100384880-C Modified peptides as therapeutic agents AMGEN INC (US) 2008-04-30 CN disclosed
CN-100384879-C Modified peptides as therapeutic agents AMGEN INC (US) 2008-04-30 CN disclosed
US-7332474-B2 Peptides and related compounds having thrombopoietic activity AMGEN INC. (US) 2008-02-19 US disclosed
EP-1144454-B1 MODIFIED PEPTIDES AS THERAPEUTIC AGENTS AMGEN INC (US) 2007-12-12 EP disclosed
EP-1439852-A4 PEPTIDES AND RELATED COMPOUNDS HAVING THROMBOPOIETIC ACTIVITY AMGEN INC (US) 2007-12-05 EP disclosed
EP-1385882-B1 PEPTIDES AND RELATED MOLECULES THAT BIND TO TALL-1 AMGEN INC (US) 2007-10-10 EP disclosed
US-20070231839-A1 Methods of treating or preventing an infectious disease using an immunogenic conjugate of a gram-negative bacterial autoinducer molecule or antibodies that immunospecifically bind a gram-negative bacterial autoinducer molecule UNIVERSITY OF ROCHESTER (US) 2007-10-04 US disclosed
US-20070231839-A1 Methods of treating or preventing an infectious disease using an immunogenic conjugate of a gram-negative bacterial autoinducer molecule or antibodies that immunospecifically bind a gram-negative bacterial autoinducer molecule UNIVERSITY OF ROCHESTER (US) 2007-10-04 US disclosed
US-20070225221-A1 Methods of treatment using specific binding agents of human angiopoietin-2 AMGEN INC. (US) 2007-09-27 US disclosed
EP-1578782-A4 COMBINATION THERAPY WITH CO-STIMULATORY FACTORS AMGEN INC (US) 2007-09-12 EP disclosed
US-7259137-B2 Tumor necrosis factors; cytokines; immunoglobulins; autoimmune diseases AMGEN INC. (US) 2007-08-21 US disclosed
WO-2007087428-A2 THROMBOPOIETIC COMPOUNDS AMGEN INC. (US) 2007-08-02 WO disclosed
US-20070149458-A1 Uses of myostatin antagonists AMGEN INC. (US) 2007-06-28 US disclosed
US-20070142295-A1 Thrombopoietic compounds AMGEN INC. (US) 2007-06-21 US disclosed
WO-2007067616-A2 USES OF MYOSTATIN ANTAGONISTS AMGEN INC (US) 2007-06-14 WO disclosed
US-20070110680-A1 Methods and compositions for controlling biofilm development MONTANA STATE UNIVERSITY (US) 2007-05-17 US disclosed
EP-1783222-A1 Dimeric thrombopoietin peptide mimetics binding to MP1 receptor and having thrombopoietic activity. Amgen Inc. (US) 2007-05-09 EP disclosed
US-20070093418-A1 Methods of treatment using specific binding agents of human angiopoietin-2 AMGEN INC. (US) 2007-04-26 US disclosed
US-20070093419-A1 Methods of treatment using specific binding agents of human angiopoietin-2 AMGEN INC. (US) 2007-04-26 US disclosed
EP-1777234-A2 Methods of treatment of inflammatory diseases using specific binding agents of human angiopoietin - 2 Amgen Inc. (US) 2007-04-25 EP disclosed
CN-1310948-C Modified peptides as therapeutic agents AMGEN INC (US) 2007-04-18 CN disclosed
US-7205275-B2 Methods of treatment using specific binding agents of human angiopoietin-2 AMGEN INC. (US) 2007-04-17 US disclosed
US-20070072801-A1 Administering peptibodies, i.e., peptides fused to other molecules such as an Fc domain of an antibody, where the peptide moiety specifically binds to Ang-2 ( angiopoietin-2); antiinflammatory agent; antirheumatic agent AMGEN INC. (US) 2007-03-29 US disclosed
EP-1767544-A2 Methods of treatment of inflammatory diseases using specific binding agents of human angiopoietin - 2 Amgen Inc. (US) 2007-03-28 EP disclosed
EP-1764370-A2 Methods of treatment of inflammatory diseases using specific binding agents of human angiopoietin - 2 Amgen Inc. (US) 2007-03-21 EP disclosed
US-20070060643-A1 Autoinducer compounds MONTANA STATE UNIVERSITY (US) 2007-03-15 US disclosed
US-7189827-B2 Modified peptides as therapeutic agents AMGEN INC. (US) 2007-03-13 US disclosed
US-7186810-B2 Modified peptides as therapeutic agents AMGEN INC. (US) 2007-03-06 US disclosed
US-20070049532-A1 Modified peptides as therapeutic agents AMGEN INC. 2007-03-01 US disclosed
CN-1908014-A Modified peptides as therapeutic agents AMGEN INC (US) 2007-02-07 CN disclosed
US-7169905-B2 Modified peptides as therapeutic agents AMGEN INC. (US) 2007-01-30 US disclosed
US-7166707-B2 Identifying peptide mimetic for treatment and prevention of tumors and autoimune diseases AMGEN INC. (US) 2007-01-23 US disclosed
US-20070010662-A1 VGF fusion polypeptides AMGEN INC. (US) 2007-01-11 US disclosed
EP-1124961-B1 THROMBOPOIETIC COMPOUNDS AMGEN INC (US) 2006-12-13 EP disclosed
US-7138370-B2 Anticancer agents; skin disorders; antiinflamamtory agents; antiarthritic agents AMGEN INC. (US) 2006-11-21 US disclosed
US-20060234307-A1 Modified peptides as therapeutic agents AMGEN INC. 2006-10-19 US disclosed
EP-0994961-B1 HOMOSERINE LACTONES BIOFILM REGULATING COMPOUNDS AND THEIR METHODS OF USE UNIV MONTANA STATE (US) 2006-10-18 EP disclosed
EP-1496926-A4 USE OF TRANSTHYRETIN PEPTIDE/PROTEIN FUSIONS TO INCREASE THE SERUM HALF-LIFE OF PHARMACOLOGICALLY ACTIVE PEPTIDES/PROTEINS AMGEN INC (US) 2006-10-18 EP disclosed
US-20060189531-A1 Thrombopoietic compounds AMGEN INC. (US) 2006-08-24 US disclosed
US-7094394-B2 Methods and compositions for controlling biofilm development MONTANA STATE UNIVERSITY (US) 2006-08-22 US disclosed
EP-1684791-A2 COMPOSITIONS AND METHODS TO MODULATE AN IMMUNE RESPONSE TO AN IMMUNOGENIC THERAPEUTIC AGENT Amgen Inc. (US) 2006-08-02 EP disclosed
US-7078435-B2 Autoinducer compounds MONTANA STATE UNIVERSITY (US) 2006-07-18 US disclosed
US-20060135431-A1 Tumor necrosis factors; cytokines; immunoglobulins; autoimmune diseases AMGEN INC. 2006-06-22 US disclosed
US-20060122370-A1 polynucleotides that code for polypeptides comprising amino acid sequences that preferentially recognize and bind to angiopoietins AMGEN INC. 2006-06-08 US disclosed
CN-1781945-A Modified peptides as therapeutic agents AMGEN INC (US) 2006-06-07 CN disclosed
CN-1781946-A Modified peptides as therapeutic agents AMGEN INC (US) 2006-06-07 CN disclosed
CN-1781947-A Modified peptides as therapeutic agents AMGEN INC (US) 2006-06-07 CN disclosed
EP-1434791-A4 SPECIFIC BINDING AGENTS OF HUMAN ANGIOPOIETIN-2 AMGEN INC (US) 2006-04-26 EP disclosed
CN-1746189-A Modified peptides as therapeutic agents AMGEN INC (US) 2006-03-15 CN disclosed
CN-1746190-A Modified peptides as therapeutic agents AMGEN INC (US) 2006-03-15 CN disclosed
US-7008924-B1 VGF fusion polypeptides AMGEN, INC. (US) 2006-03-07 US disclosed
US-7005413-B1 Combination therapy for conditions leading to bone loss AMGEN INC. (US) 2006-02-28 US disclosed
EP-1615952-A2 METHODS OF TREATMENT OF INFLAMMATORY DISEASES USING SPECIFIC BINDING AGENTS OF HUMAN ANGIOPOIETIN-2 Amgen Inc. (US) 2006-01-18 EP disclosed
CN-1721447-A Modified peptides as therapeutic agents AMGEN INC (US) 2006-01-18 CN disclosed
US-20050287152-A1 Compositions and methods to modulate an immune response to an immunogenic therapeutic agent AMGEN INC. 2005-12-29 US disclosed
EP-1487269-A4 AUTOINDUCER COMPOUNDS UNIV MONTANA STATE (US) 2005-12-21 EP disclosed
EP-1196442-B1 VGF POLYPEPTIDES AND METHODS OF TREATING VGF-RELATED DISORDERS AMGEN INC (US) 2005-12-21 EP disclosed
US-20050222035-A1 Peptides and related molecules that modulate nerve growth factor activity AMGEN INC. 2005-10-06 US disclosed
US-20050221331-A1 Osteoprotegerin AMGEN INC. 2005-10-06 US disclosed
EP-1581649-A2 BINDING AGENTS WHICH INHIBIT MYOSTATIN Amgen, Inc. (US) 2005-10-05 EP disclosed
EP-1578782-A2 COMBINATION THERAPY WITH CO-STIMULATORY FACTORS Amgen, Inc. (US) 2005-09-28 EP disclosed
EP-1385882-A4 PEPTIDES AND RELATED MOLECULES THAT BIND TO TALL-1 AMGEN INC (US) 2005-09-21 EP disclosed
EP-1578782-A3 COMBINATION THERAPY WITH CO-STIMULATORY FACTORS Amgen, Inc. (US) 2005-09-01 EP disclosed
US-6919426-B2 Peptides and related molecules that modulate nerve growth factor activity AMGEN INC. (US) 2005-07-19 US disclosed
US-20050147611-A1 Combination therapy for conditions leading to bone loss AMGEN INC. 2005-07-07 US disclosed
EP-1545581-A1 PEPTIDES AND RELATED MOLECULES THAT MODULATE NERVE GROWTH FACTOR ACTIVITY AMGEN INC. (US) 2005-06-29 EP disclosed
EP-1196188-B1 VGF SELECTIVE MONOCLONAL ANTIBODIES AND THEIR USE FOR TREATING VGF-RELATED DISORDERS AMGEN INC (US) 2005-06-22 EP disclosed
US-20050123548-A1 Modified peptides as therapeutic agents AMGEN INC. 2005-06-09 US disclosed
WO-2005044188-A2 COMPOSITIONS AND METHODS TO MODULATE AN IMMUNE RESPONSE TO AN IMMUNOGENIC THERAPEUTIC AGENT AMGEN INC. (US) 2005-05-19 WO disclosed
US-20050080014-A1 Peptides and polypeptides which may be used to increase platelets or platelet precursors (e.g., megakaryocytes) in a mammal AMGEN INC. 2005-04-14 US disclosed
US-20050049180-A1 VGF polypeptides and methods of treating VGF-related disorders AMGEN, INC. 2005-03-03 US disclosed
US-6858581-B2 Chemically-modified peptides, compositions, and methods of production and use ARIZONA STATE UNIVERSITY (US) 2005-02-22 US disclosed
EP-1496926-A1 USE OF TRANSTHYRETIN PEPTIDE/PROTEIN FUSIONS TO INCREASE THE SERUM HALF-LIFE OF PHARMACOLOGICALLY ACTIVE PEPTIDES/PROTEINS Amgen Inc. (US) 2005-01-19 EP disclosed
US-6835809-B1 Thrombopoietic compounds AMGEN INC. 2004-12-28 US disclosed
EP-1487269-A1 AUTOINDUCER COMPOUNDS Montana State University-Bozeman (US) 2004-12-22 EP disclosed
US-20040254235-A1 Autoinducer compounds NATIONAL SCIENCE FOUNDATION 2004-12-16 US disclosed
WO-2004092215-A2 METHODS OF TREATMENT OF INFLAMMATORY DISEASES USING SPECIFIC BINDING AGENTS OF HUMAN ANGIOPOIETIN-2 AMGEN INC. (US) 2004-10-28 WO disclosed
US-20040208874-A1 Combination therapy with co-stimulatory factors AMGEN, INC. 2004-10-21 US disclosed
US-20040181033-A1 Growth differentiation factor -8 binding agents for treatment of metabolic, nervous system, muscular, bone , urogenital and inflammatory disorders AMGEN, INC. 2004-09-16 US disclosed
EP-0977859-B1 THE NEUROTROPHIC FACTOR NNT-1 AMGEN INC (US) 2004-08-11 EP disclosed
EP-1439852-A1 PEPTIDES AND RELATED COMPOUNDS HAVING THROMBOPOIETIC ACTIVITY Amgen Inc. (US) 2004-07-28 EP disclosed
WO-2004060911-A2 COMBINATION THERAPY WITH CO-STIMULATORY FACTORS AMGEN INC. (US) 2004-07-22 WO disclosed
WO-2004058988-A2 BINDING AGENTS WHICH INHIBIT MYOSTATIN AMGEN, INC. (US) 2004-07-15 WO disclosed
EP-1434791-A2 SPECIFIC BINDING AGENTS OF HUMAN ANGIOPOIETIN-2 Amgen, Inc. (US) 2004-07-07 EP disclosed
US-6756404-B2 PREVENTION INFECTIONS THE RESEARCH & DEVELOPMENT INSTITUTE, INC. 2004-06-29 US disclosed
US-20040121959-A1 Peptides and related molecules that modulate nerve growth factor activity AMGEN INC. 2004-06-24 US disclosed
US-6733753-B2 ANTIINFLAMMATORY PROTEIN AMGEN INC. 2004-05-11 US disclosed
US-20040087778-A1 Modified peptides as therapeutic agents AMGEN INC. 2004-05-06 US disclosed
US-20040077022-A1 Modified peptides as therapeutic agents FEIGE ULRICH (US) 2004-04-22 US disclosed
US-20040071712-A1 Modified peptides as therapeutic agents AMGEN INC. 2004-04-15 US disclosed
WO-2004026329-A1 PEPTIDES AND RELATED MOLECULES THAT MODULATE NERVE GROWTH FACTOR ACTIVITY AMGEN INC. (US) 2004-04-01 WO disclosed
US-20040057953-A1 Modified peptides as therapeutic agents AMGEN INC. 2004-03-25 US disclosed
US-20040053845-A1 Modified peptides as therapeutic agents AMGEN INC. 2004-03-18 US disclosed
US-20040044188-A1 Modified peptides as therapeutic agents AMGEN INC. 2004-03-04 US disclosed
EP-1385882-A2 PEPTIDES AND RELATED MOLECULES THAT BIND TO TALL-1 Amgen, Inc. (US) 2004-02-04 EP disclosed
US-20030236193-A1 Methods of treatment using specific binding agents of human angiopoietin-2 AMGEN INC. 2003-12-25 US disclosed
US-20030229023-A1 Anticancer agents; skin disorders; antiinflamamtory agents; antiarthritic agents AMGEN INC. 2003-12-11 US disclosed
US-6660843-B1 Fusion of Fc domains with biologically active peptides AMGEN INC. 2003-12-09 US disclosed
US-20030207827-A1 OSTEOPROTEGERIN BOYLE WILLIAM J (US) 2003-11-06 US disclosed
WO-2003086444-A1 USE OF TRANSTHYRETIN PEPTIDE/PROTEIN FUSIONS TO INCREASE THE SERUM HALF-LIFE OF PHARMACOLOGICALLY ACTIVE PEPTIDES/PROTEINS AMGEN INC. (US) 2003-10-23 WO disclosed
US-20030195154-A1 Comprises mimetics of erythropoietin, thrombopoietin, and glucagon-like peptide conjugated to polymer AMGEN INC. 2003-10-16 US disclosed
US-6632638-B1 As a fusion partner; useful for suppressing the competing aggregation pathway and facilitating proper folding; escherichia coli AMGEN, INC. 2003-10-14 US disclosed
US-20030191056-A1 Immobilization onto polyoxyethylene glycol AMGEN INC. 2003-10-09 US disclosed
WO-2003077653-A1 AUTOINDUCER COMPOUNDS MONTANA STATE UNIVERSITY-BOZEMAN (US) 2003-09-25 WO disclosed
US-20030176352-A1 Peptides and related compounds having thrombopoietic activity AMGEN INC. 2003-09-18 US disclosed
US-20030171421-A1 Methods and compositions for controlling biofilm development MONTANA STATE UNIVERSITY 2003-09-11 US disclosed
US-6613544-B1 Secreted polypeptides; tumor necrosis factor receptor; bones; nucleic acids; recombinant vectors; host cells; drugs; bone disorders; therapy; polypeptide used to treat bone diseases such as osteoporosis AMGEN INC. 2003-09-02 US disclosed
EP-0580692-B1 AUTOINDUCER UNIV NOTTINGHAM (GB) 2003-08-13 EP disclosed
WO-2003057134-A2 SPECIFIC BINDING AGENTS OF HUMAN ANGIOPOIETIN-2 AMGEN, INC. (US) 2003-07-17 WO disclosed
US-20030105019-A1 Tumor endothelial marker 5alpha molecules and uses thereof AMGEN INC. A CORPORATION OF THE STATE OF DELAWARE 2003-06-05 US disclosed
WO-2003031589-A2 PEPTIDES AND RELATED COMPOUNDS HAVING THROMBOPOIETIC ACTIVITY AMGEN INC. (US) 2003-04-17 WO disclosed
US-20030050247-A1 Chemically-modified peptides, compositions, and methods of production and use HERCULES INCORPORATED 2003-03-13 US disclosed
EP-1278778-A2 MODIFIED PEPTIDES, COMPRISING AN FC DOMAIN, AS THERAPEUTIC AGENTS Amgen Inc., (US) 2003-01-29 EP disclosed
US-20030013755-A1 Autoinducer compounds MONTANA STATE UNIVERSITY 2003-01-16 US disclosed
EP-0994961-A4 HOMOSERINE LACTONES BIOFILM REGULATING COMPOUNDS AND THEIR METHODS OF USE UNIV MONTANA RES DEV INST (US) 2003-01-15 EP disclosed
EP-1274730-A2 INTEGRIN/ADHESION ANTAGONISTS Amgen, Inc. (US) 2003-01-15 EP disclosed
EP-1087957-A4 AUTOINDUCER COMPOUNDS UNIV MONTANA RES DEV INST (US) 2003-01-02 EP disclosed
EP-1261639-A2 CHONDROMODULIN-I RELATED PEPTIDE Amgen Inc. (US) 2002-12-04 EP disclosed
WO-2002092620-A2 PEPTIDES AND RELATED MOLECULES THAT BIND TO TALL-1 AMGEN, INC. (US) 2002-11-21 WO disclosed
US-20020168363-A1 Integrin/adhesion antagonists AMGEN INC. 2002-11-14 US disclosed
US-6455031-B1 MIXTURE OF ANALOGS OF BUTYRYL L-HOMO-SERINE LACTONE (BHL) AND BLOCKERS OF N-(3-OXODODECANOLY) L-HOMOSERINE LACTONE (ODDHL) NATIONAL SCIENCE FOUNDATION 2002-09-24 US disclosed
WO-2001003719-A9 COMBINATION THERAPY FOR CONDITIONS LEADING TO BONE LOSS AMGEN INC (US) 2002-08-08 WO disclosed
EP-1196188-A1 VGF SELECTIVE MONOCLONAL ANTIBODIES AND THEIR USE FOR TREATING VGF-RELATED DISORDERS Amgen, Inc. (US) 2002-04-17 EP disclosed
EP-1196442-A1 VGF POLYPEPTIDES AND METHODS OF TREATING VGF-RELATED DISORDERS Amgen Inc., (US) 2002-04-17 EP disclosed
US-6369027-B1 FOR THERAPY OF BONE DISEASES CHARACTERIZED BY INCREASED RESORPTION SUCH AS OSTEOPOROSIS AMGEN INC. 2002-04-09 US disclosed
US-20020009454-A1 Composition and method for treating inflammatory diseases AMGEN INC. 2002-01-24 US disclosed
CN-1331701-A Modified peptides as therapeutic agents AMGEN INC (US) 2002-01-16 CN disclosed
US-6337347-B1 ENHANCE GENE EXPRESSION IN A WIDE VARIETY OF MICROORGANISMS, THERAPEUTIC COMPOSITIONS AND THERAPEUTIC METHODS WHEREIN GENE EXPRESSION WITHIN MICROORGANISMS IS REGULATED ARE DISCLOSED. THE RESEARCH & DEVELOPMENT INSTITUTE, INC. 2002-01-08 US disclosed
WO-2001083525-A2 MODIFIED PEPTIDES, COMPRISING AN FC DOMAIN, AS THERAPEUTIC AGENTS AMGEN INC. (US) 2001-11-08 WO disclosed
WO-2001081377-A2 INTEGRIN/ADHESION ANTAGONISTS AMGEN, INC. (US) 2001-11-01 WO disclosed
EP-1144454-A2 MODIFIED PEPTIDES AS THERAPEUTIC AGENTS Amgen Inc. (US) 2001-10-17 EP disclosed
US-6294170-B1 PROTEINACEOUS IL-1 INHIBITOR (INTERLEUKIN-1RA) BY EXTENDED DELIVERY MEANS, E.G., CONTROLLED RELEASE POLYMER FORMULATIONS (HYALURONAN), IL-1RA FUSION PROTEINS AND CHEMICAL ATTACHMENT, AND CONTINUOUS PUMP INFUSION, ARTHRITIS, FUSION PROTEIN AMGEN INC. 2001-09-25 US disclosed
US-6288032-B1 POLYPEPTIDES FOR OSTEOPOROSIS AND OTHER BONE DISORDER TREATMENT AMGEN INC. 2001-09-11 US disclosed
US-6284728-B1 POLYPEPTIDE AMGEN INC. 2001-09-04 US disclosed
US-6284485-B1 GENE EXPRESSION, ENGINEERING; OSTEOPOROSIS, BONE DISORDERS; BONE RESORPTION INHIBITION; MUTANTS AMGEN INC. 2001-09-04 US disclosed
US-6284740-B1 POLYPEPTIDE AMGEN INC. 2001-09-04 US disclosed
EP-1124961-A2 THROMBOPOIETIC COMPOUNDS Amgen Inc. (US) 2001-08-22 EP disclosed
WO-2001053344-A2 CHONDROMODULIN-I RELATED PEPTIDE AMGEN, INC. (US) 2001-07-26 WO disclosed
EP-1087957-A1 AUTOINDUCER COMPOUNDS THE RESEARCH AND DEVELOPMENT INSTITUTE, INC (US) 2001-04-04 EP disclosed
WO-2001007074-A1 VGF SELECTIVE BINDING AGENTS AND METHODS OF TREATING VGF-RELATED DISORDERS AMGEN, INC. (US) 2001-02-01 WO disclosed
WO-2001007477-A1 VGF POLYPEPTIDES AND METHODS OF TREATING VGF-RELATED DISORDERS AMGEN, INC. (US) 2001-02-01 WO disclosed
WO-2001003719-A2 COMBINATION THERAPY FOR CONDITIONS LEADING TO BONE LOSS AMGEN INC. (US) 2001-01-18 WO disclosed
US-6143874-A FOR STIMULATING B-CELL AND/OR T CELL PRODUCTION; ANTIINFLAMMATORY AGENTS; TREATMENT OF ALZHEIMER'S/PARKINSON'S DISEASES, AMYOTROPHIC LATERAL SCLEROSIS, AND VARIOUS DEGENERATIVE DISORDERS THAT AFFECT VISION AMGEN INC (US) 2000-11-07 US disclosed
WO-2000024770-A9 DIMERIC THROMBOPOIETIN PEPTIDE MIMETICS BINDING TO MP1 RECEPTOR AND HAVING THROMBOPOIETIC ACTIVITY AMGEN INC (US) 2000-10-26 WO disclosed
EP-1025122-A1 FIBROBLAST GROWTH FACTOR WITH HEPATOCYTE PROLIFERATION ACTIVITY Itoh, Nobuyuki (JP) 2000-08-09 EP disclosed
WO-2000024770-A2 DIMERIC THROMBOPOIETIN PEPTIDE MIMETICS BINDING TO MP1 RECEPTOR AND HAVING THROMBOPOIETIC ACTIVITY AMGEN INC. (US) 2000-05-04 WO disclosed
WO-2000024782-A2 MODIFIED PEPTIDES, COMPRISING AN FC DOMAIN, AS THERAPEUTIC AGENTS AMGEN INC. (US) 2000-05-04 WO disclosed
EP-0994961-A2 HOMOSERINE LACTONES BIOFILM REGULATING COMPOUNDS AND THEIR METHODS OF USE The Research and development Institute, Inc (US) 2000-04-26 EP disclosed
US-6054294-A NUCLEOTIDE SEQUENCES CODING A NEURONAL POLYPEPTIDE WHICH IS INVOLVED IN THE ACTIVATION OF PROPAGATION OF NEURONS; FOR THE TREATMENT OF PARKINSON'S DISEASE AND AMYOTROPHIC LATERAL SCLEROSIS AMGEN INC. (US) 2000-04-25 US disclosed
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WO-1992018614-A1 AUTOINDUCER THE UNIVERSITY OF NOTTINGHAM (GB) 1992-10-29 WO disclosed
WO-1992018614-A1 AUTOINDUCER THE UNIVERSITY OF NOTTINGHAM (GB) 1992-10-29 WO disclosed