Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990514 | 0.84 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL6964255 | 0.81 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL6991524 | 0.78 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL29748909 | 0.77 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7619483 | 0.77 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL439345 | 0.77 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL213125 | 0.76 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL7616688 | 0.76 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL7624385 | 0.76 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL6988368 | 0.74 | PTGS2 (0.69) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6222048-B1 | AS ANTIINFLAMMATORY, ANTIPYRETIC AND ANALGESIC AGENTS; INHIBITS HORMONE INDUCED UTERINE CONTRACTION; ANTICANCER PROPERTIES; SIDE EFFECT REDUCTION | MERCK FROSST CANADA & CO. (CA) | 2001-04-24 | — | — | US | claimed |
| EP-0799218-A1 | DIARYL-2-(5H)-FURANONES AS COX-2 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1997-10-08 | — | — | EP | claimed |
| WO-1996019469-A1 | DIARYL-2-(5H)-FURANONES AS COX-2 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1996-06-27 | — | — | WO | claimed |
| US-6222048-B1 | AS ANTIINFLAMMATORY, ANTIPYRETIC AND ANALGESIC AGENTS; INHIBITS HORMONE INDUCED UTERINE CONTRACTION; ANTICANCER PROPERTIES; SIDE EFFECT REDUCTION | MERCK FROSST CANADA & CO. (CA) | 2001-04-24 | — | — | US | disclosed |
| WO-1996019469-A1 | DIARYL-2-(5H)-FURANONES AS COX-2 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1996-06-27 | — | — | WO | disclosed |