SCHEMBL7960217

SCHEMBL7960217

CO/N=C(/C=O)c1ccccc1CO/N=C(/C)c1cccc(C(F)(F)F)c1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.43
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
PPARG P37231 3/20 0.40
PPARA Q07869 3/20 0.40
NPSR1 Q6W5P4 1/20 0.38
RXFP1 Q9HBX9 3/20 0.37
GAA P10253 1/20 0.36
S1PR1 P21453 1/20 0.36
POLB P06746 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5112727 0.84 HIF1A (0.52) HIF1AKMT2AMEN1PPARGPPARA
SCHEMBL26650820 0.84 HIF1A (0.52) HIF1AKMT2AMEN1PPARGPPARA
SCHEMBL27039060 0.84 HIF1A (0.52) HIF1AKMT2AMEN1PPARGPPARA
SCHEMBL2792522 0.84 HIF1A (0.52) HIF1AKMT2AMEN1PPARGPPARA
SCHEMBL28652083 0.84 HIF1A (0.52) HIF1AKMT2AMEN1PPARGPPARA
SCHEMBL2792516 0.84 HIF1A (0.52) HIF1AKMT2AMEN1PPARGPPARA
SCHEMBL12635931 0.83 HIF1A (0.64) HIF1AKMT2AMEN1PPARGPPARA
SCHEMBL2321633 0.83 HIF1A (0.64) HIF1AKMT2AMEN1PPARGPPARA
SCHEMBL14466951 0.83 HIF1A (0.47) HIF1AKMT2AMEN1PPARGPPARA
SCHEMBL7960472 0.83 HIF1A (0.64) HIF1AKMT2AMEN1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268312-B1 FUNGICIDES SHIONOGI & CO., LTD. (JP) 2001-07-31 US disclosed
US-6048885-A FUNGICIDES SHIONOGI & CO., LTD. (JP) 2000-04-11 US disclosed