Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 6/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | IL15 | P40933 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6115916 | 0.82 | CMA1 (0.81) | CMA1TSHRSMN1; SMN2MAPTLMNA | |
| SCHEMBL18900851 | 0.82 | CMA1 (0.72) | CMA1TSHRSMN1; SMN2MAPTLMNA | |
| SCHEMBL6115028 | 0.80 | CMA1 (1.00) | CMA1TSHRMAPTLMNAHPGD | |
| SCHEMBL7965389 | 0.79 | CMA1 (0.45) | CMA1SMN1; SMN2ADRA1AHRH1ADRA1B | |
| SCHEMBL7960664 | 0.75 | HRH1 (0.66) | TSHRADRA1AHRH1ADRA1BHRH3 | |
| SCHEMBL7963507 | 0.73 | CMA1 (0.73) | CMA1TSHRSMN1; SMN2LMNAHPGD | |
| SCHEMBL18900937 | 0.69 | CMA1 (0.73) | CMA1SMN1; SMN2 | |
| SCHEMBL6115031 | 0.69 | CMA1 (0.61) | CMA1TSHRSMN1; SMN2LMNAHPGD | |
| SCHEMBL7960570 | 0.68 | CMA1 (1.00) | CMA1TSHRSMN1; SMN2 | |
| SCHEMBL143458 | 0.66 | MTNR1A (0.49) | MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010019417-A2 | CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-18 | — | — | WO | disclosed |