Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 13/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.40 |
| ▸ | PDE6D | O43924 | 1/20 | 0.40 |
| ▸ | PDE8A | O60658 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970119 | 0.79 | SLC29A1 (0.66) | SLC29A1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7976583 | 0.76 | SLC29A1 (0.71) | SLC29A1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7971739 | 0.75 | SLC29A1 (0.60) | SLC29A1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7971382 | 0.73 | HTT (0.60) | SLC29A1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7976494 | 0.72 | MAPT (0.64) | SLC29A1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7947717 | 0.71 | SLC29A1 (0.86) | SLC29A1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL31419884 | 0.70 | SLC29A1 (0.48) | SLC29A1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7948817 | 0.70 | SLC29A1 (0.57) | SLC29A1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7953158 | 0.70 | SLC29A1 (0.74) | SLC29A1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1276832 | 0.70 | SLC29A1 (0.61) | SLC29A1ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297250-B1 | USEFUL FOR INHIBITING TRANSPORT OF NUCLEOSIDES OR PURINES ACROSS CELL MEMBRANES, THEREBY TO POTENTIATE THE ACTIVITY OF VARIOUS CYTOTOXIC ANTITUMOR DRUGS | NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) | 2001-10-02 | — | — | US | disclosed |