Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960637 | 1.00 | LMNA (0.57) | LMNATP53GAAHTTTLR8 | |
| SCHEMBL7960503 | 1.00 | LMNA (0.57) | LMNATP53GAAHTTTLR8 | |
| SCHEMBL7973675 | 1.00 | LMNA (0.57) | LMNATP53GAAHTTTLR8 | |
| SCHEMBL7960627 | 1.00 | LMNA (0.57) | LMNATP53GAAHTTTLR8 | |
| Hydrochloric Acid SCHEMBL7960551 | 0.99 | LMNA (0.56) | LMNATP53GAAHTTTLR8 | |
| Hydrochloric Acid SCHEMBL7970449 | 0.99 | LMNA (0.56) | LMNATP53GAAHTTTLR8 | |
| Hydrochloric Acid SCHEMBL7973802 | 0.99 | LMNA (0.56) | LMNATP53GAAHTTTLR8 | |
| Hydrochloric Acid SCHEMBL7976606 | 0.99 | LMNA (0.56) | LMNATP53GAAHTTTLR8 | |
| Hydrochloric Acid SCHEMBL7973737 | 0.99 | LMNA (0.56) | LMNATP53GAAHTTTLR8 | |
| SCHEMBL7972073 | 0.94 | HDAC3 (0.56) | LMNATP53GAAHTTTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204264-B1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| EP-0989123-A1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-03-29 | — | — | EP | disclosed |