Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 14/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.47 |
| ▸ | PDE4A | P27815 | 6/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205164 | 0.92 | PDE4D (0.50) | PDE4DPDE4BPDE4APDE4CMEN1 | |
| SCHEMBL5056368 | 0.92 | PDE4D (0.50) | PDE4DPDE4BPDE4APDE4CMEN1 | |
| SCHEMBL7400096 | 0.92 | PDE4D (0.50) | PDE4DPDE4BPDE4APDE4CMEN1 | |
| SCHEMBL5057946 | 0.92 | PDE4D (0.50) | PDE4DPDE4BPDE4APDE4CMEN1 | |
| SCHEMBL5063706 | 0.87 | PDE4B (0.45) | PDE4DPDE4BPDE4APDE4CL3MBTL1 | |
| SCHEMBL5061811 | 0.86 | PDE4D (0.44) | PDE4DPDE4BPDE4APDE4CL3MBTL1 | |
| SCHEMBL5061814 | 0.86 | PDE4D (0.49) | PDE4DPDE4BPDE4APDE4CL3MBTL1 | |
| SCHEMBL6384297 | 0.85 | PDE4D (0.45) | PDE4DPDE4BPDE4APDE4CL3MBTL1 | |
| SCHEMBL3470159 | 0.85 | PDE4D (0.45) | PDE4DPDE4BPDE4APDE4CL3MBTL1 | |
| SCHEMBL2881473 | 0.84 | PDE4D (0.51) | PDE4DPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191138-B1 | THERAPY FOR RESPIRATORY SYSTEM DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2001-02-20 | — | — | US | disclosed |