Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 8/20 | 0.64 |
| ▸ | TPSD1 | Q9BZJ3 | 8/20 | 0.64 |
| ▸ | TPSG1 | Q9NRR2 | 8/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7483058 | 0.83 | TPSAB1 (0.64) | TPSAB1TPSD1TPSG1CYP2D6CNR1 | |
| SCHEMBL8396874 | 0.81 | TPSAB1 (0.55) | TPSAB1TPSD1TPSG1CNR1TDP1 | |
| SCHEMBL8392252 | 0.79 | TPSAB1 (0.54) | TPSAB1TPSD1TPSG1CNR1TDP1 | |
| SCHEMBL7420561 | 0.78 | TPSAB1 (1.00) | TPSAB1TPSD1TPSG1PLG | |
| SCHEMBL3791428 | 0.77 | KDM4E (0.54) | TPSAB1TPSD1TPSG1CYP2D6CNR1 | |
| SCHEMBL7413129 | 0.77 | TPSAB1 (0.68) | TPSAB1TPSD1TPSG1CYP2D6CNR1 | |
| SCHEMBL8391191 | 0.76 | TPSAB1 (0.54) | TPSAB1TPSD1TPSG1CNR1TDP1 | |
| SCHEMBL8392241 | 0.76 | HRH3 (0.54) | TPSAB1TPSD1TPSG1CYP2D6CNR1 | |
| SCHEMBL30440562 | 0.74 | CHRM3 (0.46) | TPSAB1TPSD1TPSG1CYP2D6ITGB3 | |
| SCHEMBL3249887 | 0.74 | HRH3 (0.56) | TPSAB1TPSD1TPSG1CYP2D6CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211228-B1 | COMPOUNDS WITH AMINO, GUANIDINO AND AMIDINO HETEROCYCLIC COMPOUNDS | AXYS PHARMACEUTICALS, INC | 2001-04-03 | — | — | US | disclosed |