Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 20/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140040 | 0.91 | CHEK2 (0.34) | CHEK2 | |
| SCHEMBL10140006 | 0.91 | CHEK2 (0.38) | CHEK2 | |
| SCHEMBL10140004 | 0.88 | SCD (0.36) | — | |
| SCHEMBL16258986 | 0.88 | TSPO (0.30) | — | |
| SCHEMBL10172564 | 0.85 | MAPT (0.37) | — | |
| SCHEMBL10140005 | 0.83 | PTGDR2 (0.33) | — | |
| SCHEMBL7975823 | 0.83 | HDAC3 (0.43) | — | |
| SCHEMBL7978501 | 0.83 | F10 (0.36) | — | |
| SCHEMBL7976222 | 0.82 | CHEK2 (0.44) | CHEK2 | |
| SCHEMBL7973947 | 0.81 | CHEK2 (0.36) | CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |