Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177881 | 0.99 | GAA (0.38) | GAAEPHX2TSHRHSD17B10ALOX15 | |
| SCHEMBL6176160 | 0.87 | IDH1 (0.45) | GAAEPHX2TSHRKMT2AKDM4E | |
| SCHEMBL7950687 | 0.87 | GAA (0.40) | GAAEPHX2TSHRHSD17B10ALOX15 | |
| SCHEMBL6176303 | 0.86 | GAA (0.40) | GAAEPHX2TSHRHSD17B10ALOX15 | |
| SCHEMBL6178399 | 0.86 | EPHX2 (0.43) | GAAEPHX2KMT2AKDM4EALDH1A1 | |
| SCHEMBL6175862 | 0.86 | HSD17B10 (0.40) | GAAEPHX2TSHRHSD17B10ALOX15 | |
| SCHEMBL7950958 | 0.86 | HSD17B10 (0.40) | GAAEPHX2TSHRHSD17B10ALOX15 | |
| SCHEMBL7950643 | 0.84 | GAA (0.38) | GAAEPHX2TSHRHSD17B10ALOX15 | |
| SCHEMBL6179125 | 0.84 | EPHX2 (0.39) | GAAEPHX2TSHRHSD17B10ALOX15 | |
| SCHEMBL7950813 | 0.83 | GAA (0.37) | GAAEPHX2TSHRHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |