SCHEMBL7960930

SCHEMBL7960930

Cc1ccc2c3c1cc(C(=O)NC=NN)n3CCC2O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7960920 0.85
SCHEMBL7955780 0.83
SCHEMBL7957951 0.81 CYP3A4 (0.33) SLC9A1
SCHEMBL7960892 0.80
SCHEMBL7956123 0.75 MCL1 (0.37)
SCHEMBL6798008 0.72 CA12 (0.34) SLC9A1
SCHEMBL7954089 0.72 MCL1 (0.30)
SCHEMBL7952021 0.67 MCL1 (0.47) SLC9A1
SCHEMBL6799719 0.67 KMT2A (0.36) SLC9A1
SCHEMBL7966685 0.67 BRD4 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6271251-B1 CARDIOVASCULAR DISORDERS SUMITOMO PHARMACEUTICALS COMPANY LIMITED (JP) 2001-08-07 US disclosed
US-5977100-A Substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1999-11-02 US disclosed
EP-0787728-A1 Substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1997-08-06 EP disclosed