Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | TPH1 | P17752 | 3/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CSK | P41240 | 1/20 | 0.41 |
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21117856 | 0.94 | SLC7A5 (0.44) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL20543461 | 0.94 | SLC7A5 (0.44) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL9967935 | 0.94 | SLC7A5 (0.44) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL14139328 | 0.94 | SLC7A5 (0.44) | SLC7A5ALPIPKMPTGS1XIAP | |
| L-Tyrosine Ethylester SCHEMBL9327871 | 0.93 | SLC7A5 (0.61) | SLC7A5TPH1 | |
| SCHEMBL1070138 | 0.93 | LMNA (0.51) | SLC7A5ALPIPKMPTGS1XIAP | |
| L-Tyrosine Ethylester SCHEMBL242947 | 0.93 | SLC7A5 (0.61) | SLC7A5TPH1 | |
| L-Tyrosine Ethylester SCHEMBL242946 | 0.93 | SLC7A5 (0.61) | SLC7A5TPH1 | |
| SCHEMBL839736 | 0.91 | PPARG (0.51) | SLC7A5MMP8TPH1EPHX2PPARG | |
| SCHEMBL21117877 | 0.91 | EPHX2 (0.51) | EPHX2PPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197793-B1 | VIRICIDES, BACTERICIDES, FUNGICIDES | SMITHKLINE BEECHAM CORPORATION | 2001-03-06 | — | — | US | disclosed |
| US-6030989-A | Hemoregulatory compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-29 | — | — | US | disclosed |
| EP-0861078-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1999-03-17 | — | — | EP | disclosed |
| EP-0861029-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1999-02-17 | — | — | EP | disclosed |
| EP-0861029-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-02 | — | — | EP | disclosed |
| EP-0861078-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997017965-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | disclosed |
| WO-1997017850-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | disclosed |