Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 6/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.55 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 2/20 | 0.55 |
| ▸ | PGR | P06401 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561857 | 0.86 | CYP2C19 (0.61) | CYP2C19CYP2C9EYA3MEN1ABCB11 | |
| SCHEMBL6740929 | 0.81 | CYP2C19 (0.73) | CYP2C19CYP2C9EYA3MEN1ABCB11 | |
| SCHEMBL6735773 | 0.78 | CYP2C19 (0.71) | CYP2C19CYP2C9EYA3MEN1ABCB11 | |
| SCHEMBL1287533 | 0.77 | CYP2C19 (0.73) | CYP2C19CYP2C9EYA3MEN1ABCB11 | |
| SCHEMBL9444850 | 0.77 | CYP2C19 (0.62) | CYP2C19CYP2C9EYA3MEN1ABCB11 | |
| SCHEMBL1287556 | 0.75 | CYP2C19 (1.00) | CYP2C19CYP2C9EYA3MEN1ABCB11 | |
| SCHEMBL1287913 | 0.75 | EYA3 (0.81) | CYP2C19CYP2C9EYA3MEN1ABCB11 | |
| SCHEMBL1287594 | 0.75 | CYP2C19 (0.63) | CYP2C19CYP2C9EYA3MEN1ABCB11 | |
| SCHEMBL1288122 | 0.75 | EYA3 (0.70) | CYP2C19CYP2C9EYA3MEN1ABCB11 | |
| SCHEMBL1288046 | 0.75 | CYP2C19 (0.63) | CYP2C19CYP2C9EYA3MEN1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248764-B1 | ANTIDIABETIC AGENT; HYPOGLYCEMIC AGENT | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-19 | — | — | US | disclosed |