Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14288571 | 0.81 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3SMYD3OPRM1 | |
| SCHEMBL4375995 | 0.80 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3SMYD3OPRM1 | |
| SCHEMBL4372327 | 0.80 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3SMYD3OPRM1 | |
| SCHEMBL8135217 | 0.78 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3SMYD3OPRM1 | |
| SCHEMBL1919144 | 0.78 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3SMYD3OPRM1 | |
| SCHEMBL4632632 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3SMYD3OPRM1 | |
| Hydrochloric Acid SCHEMBL6543165 | 0.77 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3SMYD3OPRM1 | |
| Hydrochloric Acid SCHEMBL5810068 | 0.76 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3SMYD3OPRM1 | |
| SCHEMBL8347656 | 0.75 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3SMYD3OPRM1 | |
| Hydrochloric Acid SCHEMBL8350781 | 0.74 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3SMYD3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303620-B1 | USED FOR THERAPY OF MEDICAL DISORDERS RESULTING FROM A DEFICIENCY IN GROWTH HORMONE | NOVO NORDISK A/S (DK) | 2001-10-16 | — | — | US | disclosed |